Department of Oral and Maxillofacial Surgery, Division of Reparative and Regenerative Medicine, Institute of Medical Science, Mie University Graduate School of Medicine, Japan.
Aust Dent J. 2010 Jun;55(2):200-2. doi: 10.1111/j.1834-7819.2010.01211.x.
Graft-versus-host disease (GVHD) can occur at various sites, including the oral mucosa, where it is associated with a high risk of head and neck cancer. We report the case of a 46-year-old woman with tongue cancer that developed following Hodgkin's lymphoma and chronic GVHD, and we discuss the possible causes of cancer development.
移植物抗宿主病(GVHD)可发生于多个部位,包括口腔黏膜,而口腔黏膜 GVHD 与头颈部癌症风险升高相关。我们报告了一例霍奇金淋巴瘤及慢性 GVHD 后继发舌癌的 46 岁女性病例,并讨论了癌症发生的可能原因。