State Key Laboratory of Oral Diseases, Sichuan University, Chengdu, China.
Int J Oral Maxillofac Surg. 2010 Sep;39(9):878-82. doi: 10.1016/j.ijom.2010.04.048. Epub 2010 Jun 3.
The aim of this research is to analyze the prevalence of dentigerous cysts (DCs) in a population-based cohort in British Columbia, Canada, and to report unusual cases associated with DC. The database of the British Columbia Oral Biopsy Service was searched from 1998 to 2007. 2082 histologically confirmed DCs from 2029 patients were retrieved and retrospectively analyzed for incidence, age, gender and ethnicity. The results show that this is a common jaw cyst with male predilection, has a peak incidence in younger adults and is more common in Caucasians. Multiple DCs, representing 2.5% of the cases, are not associated with any syndromes or systemic conditions. 0.5% DCs were associated with other cysts or tumours at the same site or the opposite side of the jaw. The authors report the first series of cases presenting clinically as bilateral DCs, but histologically as an odontogenic tumour or another type of odontogenic cyst. DCs can co-exist with other more serious conditions, such as odontogenic keratocyst or cystic ameloblastoma. This association with more significant conditions indicates the importance of histologically confirming any jaw cyst, even when it presents clinically as a classic DC.
本研究旨在分析加拿大不列颠哥伦比亚省基于人群的队列中齿龈囊肿（DCs）的流行情况，并报告与 DC 相关的罕见病例。从 1998 年到 2007 年，对不列颠哥伦比亚口腔活检服务数据库进行了搜索。从 2029 名患者中获取并回顾性分析了 2082 例经组织学证实的 DCs，以分析其发病率、年龄、性别和种族。结果表明，这是一种常见的颌骨囊肿，男性易患，在年轻成年人中发病率较高，在白种人中更为常见。多发性 DCs 占病例的 2.5%，与任何综合征或系统性疾病无关。0.5%的 DCs 与同一部位或颌骨对侧的其他囊肿或肿瘤有关。作者报告了首例临床上表现为双侧 DCs、但组织学上表现为牙源性肿瘤或另一种牙源性囊肿的病例系列。DCs 可与其他更严重的疾病共存，如牙源性角化囊肿或囊性成釉细胞瘤。这种与更严重疾病的关联表明，即使临床上表现为典型的 DCs，也需要通过组织学确认任何颌骨囊肿。
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