Suppr超能文献

经高尔基体。

Passage through the Golgi.

机构信息

Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.

出版信息

Curr Opin Cell Biol. 2010 Aug;22(4):471-8. doi: 10.1016/j.ceb.2010.05.003. Epub 2010 Jun 3.

Abstract

There are, in theory, several ways in which proteins may pass through the Golgi apparatus. Among these, the cisternal progression-maturation mode has gained broad consensus. However, there remain questions regarding the molecular mechanisms by which resident proteins are sorted from cargo and move backward to the proximal cisterna in synchrony with cisternal progression. In this short review, we discuss current questions about the organisation of trafficking to, through, and out of the Golgi apparatus, as well as the main approaches being developed to address such questions in model organisms including yeast, mammals and plants.

摘要

理论上,蛋白质可能通过高尔基体的方式有几种。其中,小泡运输-成熟模式得到了广泛的共识。然而,对于驻留蛋白如何与货物分离并与小泡运输同步向后移动到近侧小泡腔,以及分子机制仍存在问题。在这篇简短的综述中,我们讨论了当前关于高尔基体运输、通过和输出的组织以及主要方法的问题,包括酵母、哺乳动物和植物等模式生物中解决这些问题的主要方法。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验