School of Medicine and Pharmacology, University of Western Australia, Australia.
Int J Obstet Anesth. 2010 Jul;19(3):282-6. doi: 10.1016/j.ijoa.2010.01.001. Epub 2010 Jun 3.
Hypotension after spinal anaesthesia is a common and important complication at caesarean delivery. Skin conductance monitoring has been shown to predict post-spinal hypotension in elderly patients and may be a rapid, non-invasive means of predicting risk in the obstetric population.
Women having elective caesarean delivery were included in this observational pilot trial. Baseline data were obtained for blood pressure, heart rate and skin conductance variables before administration of spinal anaesthesia and at 1-min intervals for 20 min thereafter. Correlations between baseline data and minimum post-spinal blood pressure were calculated, and the predictive value of baseline variables was estimated by use of receiver operator characteristics.
Forty women completed the study. Spinal anaesthesia was followed in most cases by a significant reduction from baseline in systolic blood pressure [0-9% n=2 (5%), 10-20% n=21 (52.5%), 20-30% n=12 (30%), >30% n=5 (12.5%)]. Minimum systolic blood pressure was >100 mmHg in 25 (62%), 80-100 mmHg in 12 (30%) and < 80 mmHg in 3 (7.5%) patients. Fasting times, spinal block distribution, baseline heart rate, blood pressure or baseline skin conductance did not predict post-spinal hypotension or neonatal outcome.
In contrast to a previous report in elderly patients, we were unable to demonstrate a significant relationship between baseline sympathetic tone, measured by skin conductance, and hypotension following spinal anaesthesia in women undergoing elective caesarean delivery.
椎管内麻醉后低血压是剖宫产的常见且重要的并发症。皮肤电导监测已被证明可预测老年患者椎管内麻醉后低血压,并且可能是预测产科人群风险的快速、非侵入性方法。
本观察性初步试验纳入了行择期剖宫产的女性。在给予椎管内麻醉前和此后 20 分钟内每隔 1 分钟记录血压、心率和皮肤电导变量的基线数据。计算了基线数据与椎管内麻醉后最低血压之间的相关性,并通过接受者操作特征估计基线变量的预测价值。
40 名女性完成了研究。大多数情况下,椎管内麻醉后收缩压从基线显著下降[0-9% n=2(5%),10-20% n=21(52.5%),20-30% n=12(30%),>30% n=5(12.5%)]。25 名(62%)患者的最低收缩压>100mmHg,12 名(30%)患者的最低收缩压为 80-100mmHg,3 名(7.5%)患者的最低收缩压<80mmHg。禁食时间、脊髓阻滞分布、基线心率、血压或基线皮肤电导均不能预测椎管内麻醉后低血压或新生儿结局。
与老年患者的先前报告相反,我们未能证明在接受择期剖宫产的女性中,基线交感神经张力(通过皮肤电导测量)与椎管内麻醉后低血压之间存在显著关系。