Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA, USA.
Rev Neurol (Paris). 2010 Dec;166(12):978-86. doi: 10.1016/j.neurol.2010.03.024. Epub 2010 Jun 1.
Optical coherence tomography (OCT) is a non-invasive imaging technique routinely used in ophthalmology to visualize and quantify the layers of the retina. It also provides information on optic nerve head topography, peripapillary retinal nerve fiber layer thickness, and macular volume, which correlate with axonal loss. These measurements are of particular interest in optic neuropathies and in multiple sclerosis, and OCT parameters are now used as endpoints in neurologic clinical trials.
光学相干断层扫描(OCT)是一种眼科常用的非侵入性成像技术,用于可视化和量化视网膜的各层。它还提供有关视神经头形态、视盘周围视网膜神经纤维层厚度和黄斑体积的信息,这些信息与轴突丢失相关。这些测量在神经病变和多发性硬化症中特别有意义,OCT 参数现在已被用作神经病学临床试验的终点。