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经食管超声心动图对慢性心房颤动患者左心房自发对比回声与脑栓塞关系的研究

[A study on the relationship between spontaneous contrast echoes in left atrium and cerebral embolism in patients with chronic atrial fibrillation by using transesophageal echocardiography].

作者信息

Hirabayashi T

机构信息

Department of Cardiovascular Medicine, Hokkaido University School of Medicine, Sapporo, Japan.

出版信息

Hokkaido Igaku Zasshi. 1991 Mar;66(2):179-86.

PMID:2060906
Abstract

We assessed the relationship between the presence of spontaneous eotrast echoes (SCEs) in left atrium (LA) and the incidence of cerebral embolism. Transesophageal echocardiography (TEE) was performed in 56 patients (36 male, age 69.6 +/- 8.9 yrs.) with non-valvular chronic atrial fibrillation (NVAF), In 37 patients (66.1%), SCEs were detected by TEE, However, SCEs could not be detected in any patients by transthoracic echocardiography (TTE). In 9 patients (16.1%), left atrial thrombi were detected by TEE, but they could not be detected by TTE. According to the degree of SCEs, the patients were divided into three groups as follows; Group (-) (n = 19): SCEs were not detectable, Group (mild) (n = 17): SCEs were detectable in part of LA, Group (marked) (n = 20): SCEs were detectable in whole LA. LA thrombi were detected in 1 (5%) of the Group (-) patients, 2 (12%) of the Group (mild) patients and 6 (30%) of the Group (marked) patients (p = NS). 17 patients had a history of cerebral embolism. In Group (-), only one patient (5%) had a history of cerebral embolism. But 4 patients (24%) of Group (mild) and 12 patients (60%) of Group (marked) had histories of cerebral embolism. The incidence of cerebral embolism was significantly higher in Group (marked) than Group (-) (P less than 0.01) and Group (mild) (P less than 0.05). We conclude that, in patients with NVAF, the presence of SCEs by TEE may be a useful variable in identifying increased risk of cerebral embolism.

摘要

我们评估了左心房(LA)内自发性造影剂回声(SCEs)的存在与脑栓塞发生率之间的关系。对56例(36例男性,年龄69.6±8.9岁)非瓣膜性慢性心房颤动(NVAF)患者进行了经食管超声心动图(TEE)检查。37例(66.1%)患者经TEE检测到SCEs,然而,经胸超声心动图(TTE)在所有患者中均未检测到SCEs。9例(16.1%)患者经TEE检测到左心房血栓,但TTE未检测到。根据SCEs的程度,将患者分为以下三组:(-)组(n = 19):未检测到SCEs;(轻度)组(n = 17):左心房部分可检测到SCEs;(显著)组(n = 20):整个左心房均可检测到SCEs。(-)组患者中有1例(5%)检测到左心房血栓,(轻度)组有2例(12%),(显著)组有6例(30%)(p =无显著性差异)。17例患者有脑栓塞病史。(-)组中只有1例患者(5%)有脑栓塞病史。但(轻度)组有4例患者(24%),(显著)组有12例患者(60%)有脑栓塞病史。(显著)组脑栓塞的发生率显著高于(-)组(P<0.01)和(轻度)组(P<0.05)。我们得出结论,在NVAF患者中,TEE检测到SCEs可能是识别脑栓塞风险增加的一个有用变量。

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