Nanavaty Mayank A, Spalton David J, Boyce James, Vasavada Abhay R
Department of Ophthalmology, St. Thomas' Hospital, Rayne Institute, Kings College, London, United Kingdom.
J Cataract Refract Surg. 2010 Jul;36(7):1135-41. doi: 10.1016/j.jcrs.2010.01.021.
To evaluate the natural history of focal collections (islands) of lens epithelial cells (LECs) on the posterior capsule after cataract surgery.
Department of Ophthalmology, St. Thomas' Hospital, London, United Kingdom.
Patients in previous studies with various intraocular lenses (IOLs) and at least a 2-year follow-up were identified. Postoperative digital retroillumination images of each eye taken at 1, 3, and 6 months and 1 and 2 years were assessed for the presence of LEC islands and their incidence, etiology, time of appearance, change with time, and relationship to IOL material.
Islands of LECs were identified in 39 eyes with an AcrySof SA60AT IOL, 40 eyes with a Rayner Centerflex C570H IOL, and 27 eyes with a Hoya YA60BB IOL. In all groups, the islands tended to appear within 6 months with a decreasing incidence thereafter. Floating LECs that seeded on the posterior capsule (seeded LECs) or LECs left on the posterior capsule at surgery were seen in a small number of eyes. Most islands were derived from regression of a previous LEC membrane, and a majority continued to regress. Intraocular lens material had no influence on the natural history or morphology of the islands.
Islands of LECs were common postoperatively. Equatorial LECs appeared to be the major cause of clinical posterior capsule opacification (PCO). Floating LECs in the aqueous that seeded on the posterior capsule or LECs left behind after surgery did not appear to contribute to clinical PCO.
No author has a financial or proprietary interest in any material or method mentioned.
评估白内障手术后晶状体上皮细胞（LECs）在后囊膜上的局灶性聚集（小岛）的自然病程。
英国伦敦圣托马斯医院眼科。
确定先前研究中植入各种人工晶状体（IOL）且随访至少2年的患者。评估在术后1、3、6个月以及1年和2年拍摄的每只眼睛的数字后照图像，以确定LEC小岛的存在及其发生率、病因、出现时间、随时间的变化以及与IOL材料的关系。
在39只植入AcrySof SA60AT IOL的眼睛、40只植入Rayner Centerflex C570H IOL的眼睛和27只植入Hoya YA60BB IOL的眼睛中发现了LEC小岛。在所有组中，小岛往往在6个月内出现，此后发生率逐渐降低。在少数眼睛中可见漂浮在后囊膜上的LECs（播种LECs）或手术时留在后囊膜上的LECs。大多数小岛源自先前LEC膜的消退，并且大多数继续消退。IOL材料对小岛的自然病程或形态没有影响。
LEC小岛在术后很常见。赤道部LECs似乎是临床后囊膜混浊（PCO）的主要原因。房水中漂浮并播种在后囊膜上的LECs或手术后残留的LECs似乎对临床PCO没有影响。
没有作者对文中提及的任何材料或方法拥有财务或专利权益。
