Ostler H B, Thygeson P, Okumoto M, Weddell J
Am Fam Physician. 1978 Apr;17(4):134-40.
Since corticosteroids were introduced, a steadily increasing number of opportunistic pathogens have been causing major disease in both systemically and locally compromised hosts. In ocular disease, the most common cause of compromise (and of infection with such opportunistic pathogens as the herpeviruses, many gram-negative bacteria, numerous fungi and Toxoplasma) is the topical use of corticosteroids and antibiotic-corticosteroid preparations. To avoid the damaging and sometimes blinding results of opportunistic infection, the use of these preparations should be carefully restricted.
自从引入皮质类固醇以来，越来越多的机会性病原体在全身和局部免疫功能受损的宿主中引发重大疾病。在眼部疾病中，最常见的免疫功能受损原因（以及感染疱疹病毒、许多革兰氏阴性菌、多种真菌和弓形虫等机会性病原体的原因）是局部使用皮质类固醇和抗生素 - 皮质类固醇制剂。为避免机会性感染造成的损害甚至失明后果，应谨慎限制这些制剂的使用。
