Little B B, Buschang P H, Malina R M
Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas 75235-9032.
J Craniofac Genet Dev Biol. 1991 Jan-Mar;11(1):18-23.
Gene flow is associated with differences in craniofacial and postcranial dimensions among indigenous populations of southern Mexico. This study compares four craniofacial dimensions in 322 children from families which have an average inbreeding coefficient of 0.01 and 36 children from families which have an inbreeding coefficient of zero (more heterozygous) in a Zapotec speaking community. In addition, two indices were computed. With sex and chronological age constant, there is a statistically significant difference between more and less heterozygous children in bizygomatic diameter. Differences in biparietal diameter and fronto-occipital length reflect the same tendency. The differences probably reflect more an effect of heterozygosity on these dimensions than facial dissimilarity of the populations from which the new genetic materials were drawn because gene flow was from related groups of Indians (e.g., Mixtec) in southern Mexico. Hence, midface growth and overall normal size appear to be affected by fluctuation in level of heterozygosity.
基因流动与墨西哥南部土著居民颅面和颅后尺寸的差异有关。本研究比较了来自平均近亲繁殖系数为0.01的家庭的322名儿童和来自近亲繁殖系数为零(杂合性更高)的家庭的36名儿童在一个说萨波特克语社区中的四个颅面尺寸。此外,还计算了两个指数。在性别和实足年龄恒定的情况下,杂合性较高和较低的儿童在颧骨间直径上存在统计学上的显著差异。双顶径和额枕长度的差异反映了相同的趋势。这些差异可能更多地反映了杂合性对这些尺寸的影响,而不是新基因材料来源人群的面部差异,因为基因流动来自墨西哥南部相关的印第安人群体(如米斯特克人)。因此,面中部生长和整体正常大小似乎受到杂合性水平波动的影响。