Ohte N, Nakano S, Hashimoto T, Narita H, Hayano J, Fujinami T
Third Department of Internal Medicine, Nagoya City University Medical School, Japan.
Jpn Circ J. 1991 May;55(5):459-64. doi: 10.1253/jcj.55.459.
Left ventricular performance was evaluated in 51 patients with acute myocardial infarction and angina pectoris using parameters derived from the flow velocity waveform at the ascending aorta. Flow velocity waveforms were obtained from the suprasternal notch by continuous-wave Doppler echocardiography and were recorded on a line-scan recorder at a paper speed of 100 mm/sec with lead II ECG. The peak flow velocity and the systolic time interval from the beginning of ECG Q wave to the peak flow velocity (Q-V peak interval) were measured. Relationships were investigated between these parameters and the left ventricular ejection fraction (LVEF) obtained from multigated equilibrium blood pool imaging with 99mTc-pertechnetate. The peak flow velocity did not correlate with LVEF (r = 0.27). However, a highly significant negative correlation was observed between the systolic time interval Q-V peak and LVEF (r = -0.84, p less than 0.001). The regression equation was LVEF = -0.46 X (Q-V peak) + 142. We conclude that left ventricular performance can be evaluated in patients with coronary artery disease at the bedside using the Q-V peak interval measured from simultaneous recording of the velocity waveform at the ascending aorta and the ECG.
利用升主动脉处血流速度波形得出的参数，对51例急性心肌梗死和心绞痛患者的左心室功能进行了评估。通过连续波多普勒超声心动图从胸骨上切迹获取血流速度波形，并以100mm/秒的纸速记录在带有II导联心电图的线阵记录仪上。测量了峰值血流速度以及从心电图Q波开始到峰值血流速度的收缩期时间间隔（Q-V峰值间隔）。研究了这些参数与通过99m锝高锝酸盐多门控平衡血池显像获得的左心室射血分数（LVEF）之间的关系。峰值血流速度与LVEF无相关性（r = 0.27）。然而，收缩期时间间隔Q-V峰值与LVEF之间观察到高度显著的负相关（r = -0.84，p < 0.001）。回归方程为LVEF = -0.46×（Q-V峰值）+ 142。我们得出结论，利用同时记录的升主动脉处速度波形和心电图测量的Q-V峰值间隔，可在床边对冠心病患者的左心室功能进行评估。
