Robinson Nicholas A, Armíen Aníbal G
Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, 1333 Gortner Avenue, St. Paul, MN 55108, USA.
J Vet Diagn Invest. 2010 Jul;22(4):667-70. doi: 10.1177/104063871002200433.
A Bulldog puppy that died at 1 day of age was presented for postmortem evaluation. Macroscopically, there was marked hypoplasia of the ascending, transverse, and proximal segments of the descending thoracic aorta and almost complete secondary thrombosis of the left ventricle causing a functional stenosis of the left atrioventricular valve. Separately, there was right atrioventricular valve dysplasia with secondary dilation of the right atrium. Microscopically, the left ventricular outflow tract was occluded by chondroid metaplasia, fibrosing recanalization of a left-ventricular thrombus, and isolated Purkinje fiber degeneration and necrosis.
一只1日龄死亡的斗牛犬幼犬被送来进行尸检。宏观上，升主动脉、横主动脉和降主动脉近端节段明显发育不全，左心室几乎完全继发血栓形成，导致左房室瓣功能性狭窄。另外，存在右房室瓣发育异常并伴有右心房继发性扩张。微观上，左心室流出道被软骨样化生、左心室血栓的纤维性再通以及孤立的浦肯野纤维变性和坏死所阻塞。
