Department of Medicine, and the Centre on Aging, Section of Geriatric Medicine, University of Manitoba, Canada.
Int J Geriatr Psychiatry. 2010 Aug;25(8):814-21. doi: 10.1002/gps.2422.
Quality of life in dementia has been studied in clinical settings. There is less population-based research on life satisfaction and cognition.
(1) To compare the overall life satisfaction (LS), LS with material circumstances (LS (material)), and LS with social circumstances (LS (social)) of older adults with no cognitive impairment, with cognitive impairment no dementia (CIND), and with dementia; (2) To examine the effect of cognition on LS across a broad spectrum of cognition; and (3) To explore the effect of factors such as depressive symptoms, functional impairment, education, and social support.
1620 community-dwelling older adults with a mini-mental state examination (MMSE) score > 10, sampled from a representative list were interviewed.
Age, gender, education, social networks, and social supports were all self-reported. The MMSE, the Centre for Epidemiologic Studies-Depression (CES-D), and the Older Americans Resource Survey (OARS) were used. Dementia was diagnosed by clinical examination using DSM-IIIR criteria. LS was measured using the Terrible-Delightful Scale. Factor analysis identified two factors: LS (material), and LS (social). A global item measuring overall LS was also used.
Those with dementia and CIND had lower LS than those with normal cognition, but the effect was relatively small. There was a gradient in LS which extended into the normal range of cognition. Depressive symptoms and functional status were strongly associated with LS.
Cognition is associated with LS, but the effect is fairly small. Most older adults are satisfied with life.
在临床环境中已经研究了痴呆症患者的生活质量。针对认知功能正常的人群，关于生活满意度和认知功能的研究相对较少。
（1）比较无认知障碍、认知障碍但非痴呆（CIND）和痴呆老年人的总体生活满意度（LS）、物质状况下的 LS（LS（物质））和社会状况下的 LS（LS（社会））；（2）研究认知功能对广泛认知范围内 LS 的影响；（3）探讨抑郁症状、功能障碍、教育和社会支持等因素的影响。
从具有>10 分的简易精神状态检查（MMSE）得分的代表性名单中，抽取了 1620 名居住在社区的认知功能正常的老年人进行访谈。
年龄、性别、教育、社交网络和社会支持均为自我报告。使用 MMSE、流行病学研究中心抑郁量表（CES-D）和老年人资源调查（OARS）进行评估。采用 DSM-III-R 标准进行临床检查诊断痴呆。使用 Terrible-Delightful 量表测量 LS。因子分析确定了两个因素：LS（物质）和 LS（社会）。还使用了一个测量总体 LS 的综合项目。
痴呆症和 CIND 患者的 LS 低于认知功能正常的患者，但影响相对较小。LS 呈梯度下降，甚至延伸到认知正常范围。抑郁症状和功能状态与 LS 密切相关。
认知与 LS 相关，但影响相当小。大多数老年人对生活感到满意。
