Department of Pharmacology, Jessenius Faculty of Medicine in Martin, Comenius University, Sklabinska 26, SK 037 53, Martin, Slovakia.
Fitoterapia. 2010 Dec;81(8):1037-44. doi: 10.1016/j.fitote.2010.06.027. Epub 2010 Jul 17.
(Glucurono)arabinoxylans were extracted from the wheat bran with acetate buffer in the first step (WBH1) and with dilute alkali in the second step (WBH2). In both samples xylose and arabinose dominated, accompanied with smaller amounts of galactose, glucose, mannose and uronic acids mainly in WBH1. WBH1 was free of protein and with low content of phenolic compounds. Fraction WBH2 contained relatively low levels of proteins and about 4.5% of the total phenolic. When tested for antitussive activity, the (glucurono)arabinoxylans exhibited comparable cough-suppressing effect with centrally acting codeine. The observed effects of bronchoconstriction are limiting practical application of WBH2.
（葡糖醛酸）阿拉伯木聚糖先用醋酸缓冲液从麦麸中提取（WBH1），然后第二步用稀碱提取（WBH2）。在这两个样品中，木糖和阿拉伯糖占主导地位，其次是少量的半乳糖、葡萄糖、甘露糖和主要存在于 WBH1 中的糖醛酸。WBH1 不含蛋白质，酚类化合物含量低。分馏得到的 WBH2 含有相对较低水平的蛋白质和约 4.5%的总酚类物质。当用于镇咳活性测试时，（葡糖醛酸）阿拉伯木聚糖表现出与中枢作用的可待因相当的镇咳效果。观察到的支气管收缩作用限制了 WBH2 的实际应用。
