Yeomans A C
Division of Medical, University of Texas M.D. Anderson Cancer Center, Houston.
Nurse Pract. 1991 Apr;16(4):18, 21, 25-6.
Gout is a metabolic disorder of purine metabolism that leads to elevated serum concentrations of uric acid. When this happens, urate crystals may precipitate and accumulate in the joints and bursae. Gout is characterized by recurrent, painful attacks of arthritis, which is the major clinical complication of the disease. Early diagnosis and treatment of gout are important to prevent complications, and with early, sustained therapy, most patients can live without functional disability. If gout becomes chronic, individuals may experience severe limitations of activity. This article discusses the clinical manifestations, diagnosis and treatment of acute and chronic gout.
痛风是一种嘌呤代谢的代谢紊乱疾病，会导致血清尿酸浓度升高。当这种情况发生时，尿酸盐结晶可能会沉淀并积聚在关节和滑囊中。痛风的特征是反复发作的疼痛性关节炎发作，这是该疾病的主要临床并发症。痛风的早期诊断和治疗对于预防并发症很重要，并且通过早期、持续的治疗，大多数患者可以在没有功能残疾的情况下生活。如果痛风变为慢性，个体可能会经历严重的活动受限。本文讨论急性和慢性痛风的临床表现、诊断和治疗。
