College of Medicine, University of South Alabama, Mobile, AL 366, USA.
Pediatrics. 2010 Aug;126(2):e479-82. doi: 10.1542/peds.2009-2303. Epub 2010 Jul 12.
Gliomatosis cerebri (GC) is a diffuse infiltrating glial neoplasm of astrocytic origin. GC in children is rare and difficult to diagnose, often presenting with a variety of signs and symptoms that may mimic encephalitis. We discuss here the presentation and diagnosis of GC in 2 children who were initially suspected to have acute disseminating encephalomyelitis. In this report we underscore the limitations of relying on clinical presentation and neuroimaging as well as the essential role of pathologic evaluation for the diagnosis of GC in children.
脑胶质瘤病（Gliomatosis cerebri，GC）是一种源自星形胶质细胞的弥漫浸润性神经胶质瘤。儿童脑胶质瘤病较为罕见，且难以诊断，其常表现出多种可能与脑炎相混淆的体征和症状。本文探讨了 2 例最初疑似急性播散性脑脊髓炎的儿童患者的 GC 临床表现和诊断。本报告强调了仅依靠临床表现和神经影像学的局限性，以及病理评估对于儿童 GC 诊断的重要性。
