Moreno R J, Kloess P, Carlson D W
Department of Ophthalmology, Wilford Hall USAF Medical Center, Lackland AFB, TX 78236-5300.
Ophthalmology. 1991 May;98(5):636-8. doi: 10.1016/s0161-6420(91)32240-1.
The use of succinylcholine in patients with suspected or proven open globes is considered dangerous by some for fear of extruding the intra-ocular contents as a consequence of the co-contraction of the extraocular muscles it produces. To test this hypothesis, the authors devised an anterior and a posterior trauma model in the cat eye. Thirty events were studied using the anterior trauma model and eight with the posterior model. The only observable effect of succinylcholine administration was forward displacement of the lens and iris. No intraocular content was lost in any event. The authors believe this study supports the argument that, when indicated, succinylcholine may be considered in open globes.
对于疑似或已证实存在开放性眼球损伤的患者，使用琥珀酰胆碱被一些人认为是危险的，因为担心它会引起眼外肌共同收缩，从而挤出眼内内容物。为了验证这一假设，作者在猫眼上设计了一种前部和一种后部创伤模型。使用前部创伤模型研究了30例，使用后部模型研究了8例。给予琥珀酰胆碱后唯一可观察到的效应是晶状体和虹膜向前移位。在任何一例中均未出现眼内内容物丢失。作者认为这项研究支持这样的观点，即当有指征时，在开放性眼球损伤患者中可以考虑使用琥珀酰胆碱。
