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中药穴位贴敷治疗变应性鼻炎的随机对照临床试验。

Chinese medicine acupoint herbal patching for allergic rhinitis: a randomized controlled clinical trial.

机构信息

Department of Traditional Chinese Medicine, Potz Hospital, Executive Yuan, Taiwan.

出版信息

Am J Chin Med. 2010;38(4):661-73. doi: 10.1142/S0192415X10008135.

Abstract

The aim of this study is pursue the effect of herbal point-patch treatment on allergic rhinitis patients by investigation of the changes of serum total IgE (T-IgE) and eosinophile cationic protein (ECP) levels and through assessment of the results of SF-36 and rhinitis severity questionnaires. A prospective, randomized, single-blind, parallel, controlled study was used. Forty- three eligible participants were selected from outpatients of the Dept. of Ear, Nose, and Throat and Chinese medicine clinic, and 33 eligible participants completed the treatment satisfactorily. Participants used a Chinese herbal point-patch or a placebo patch once a week, for three hours at a time, after being randomly assigned to a control or an experimental group. Each treatment course was three weeks in duration, and each participant underwent two courses of treatment. Before and after each course, participants evaluated the effectiveness of the treatment by completing a questionnaire, and blood samples were collected for T-IgE and ECP analysis. The data revealed that the acupoint herbal patch is a valuable treatment for allergic rhinitis, especially in the symptoms of sneezing, running and itchy nose. The results of the SF-36 indicate a distinct improvement in GH (general health) and VT (vitality) in patients treated with acupoint herbal patches. This study supports the belief that the acupoint herbal patch is an effective treatment for allergic rhinitis and can significantly improve general health, social life and vitality in quality of life.

摘要

本研究旨在通过观察血清总 IgE(T-IgE)和嗜酸性粒细胞阳离子蛋白(ECP)水平的变化,并通过 SF-36 和鼻炎严重程度问卷的评估结果,探讨中药穴位贴敷治疗变应性鼻炎的疗效。采用前瞻性、随机、单盲、平行对照的研究方法。从耳鼻喉科门诊和中医门诊中选择 43 名符合条件的患者,随机分为对照组和实验组,每组 21 例,每组各有 21 例患者完成了治疗。患者每周使用一次中药穴位贴敷或安慰剂贴敷,每次 3 小时。每个疗程为 3 周,每个患者接受两个疗程的治疗。在每个疗程前后,患者通过填写问卷评估治疗效果,并采集血样进行 T-IgE 和 ECP 分析。数据显示,穴位贴敷是治疗变应性鼻炎的有效方法,尤其是在打喷嚏、流涕和鼻痒症状方面。SF-36 结果表明,穴位贴敷治疗组的 GH(一般健康)和 VT(活力)明显改善。本研究支持穴位贴敷是治疗变应性鼻炎的有效方法的观点,能显著改善患者的一般健康、社会生活和活力方面的生活质量。

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