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心脏移植后因心动过速性心肌病导致的心源性休克:伊伐布雷定治疗成功

Cardiogenic shock due to tachycardiomyopathy after heart transplantation: successful treatment with ivabradine.

作者信息

Zwicker C, Becker M, Lepper W, Koch K C, Westenfeld R

机构信息

Department of Cardiology, University Hospital Aachen, Aachen, Germany.

出版信息

Cardiology. 2010;116(3):174-7. doi: 10.1159/000318530. Epub 2010 Jul 13.

Abstract

Tachycardia-induced cardiomyopathy refers to an impairment in left-ventricular function due to chronic or prolonged tachycardia. We describe a heart transplant patient who developed cardiogenic shock due to tachycardia-induced cardiomyopathy. Low-output failure was further aggravated by administration of a short-acting beta-blocker during invasive hemodynamic monitoring. In contrast, heart rate control by administration of increasing doses of ivabradine supported recovery from cardiogenic shock and led to an improvement in the patient's clinical condition as well as left-ventricular function during follow-up.

摘要

心动过速性心肌病是指由于慢性或持续性心动过速导致的左心室功能损害。我们描述了一名心脏移植患者,其因心动过速性心肌病而发生心源性休克。在有创血流动力学监测期间,给予短效β受体阻滞剂进一步加重了低心排血量衰竭。相比之下,通过给予递增剂量的伊伐布雷定来控制心率有助于心源性休克的恢复,并在随访期间使患者的临床状况以及左心室功能得到改善。

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