Department of Orthopaedic Surgery, University of Louisville School of Medicine, Louisville, KY, USA.
Spine (Phila Pa 1976). 2010 Aug 1;35(17):1621-8. doi: 10.1097/BRS.0b013e3181ce11cc.
Literature-based topic review.
To review the complications and the concerns that may be associated with all of the commonly used osteobiologic options for spine fusion.
Obtaining a solid arthrodesis is an important objective in many lumbar surgical procedures, and a wide array of bone graft materials may be used in an attempt to achieve this goal. Iliac crest bone graft, as well as all of the available osteobiologic alternatives, carries potential risks and concerns for both patient and surgeon.
Review of literature and expert opinion.
Some of the potential complications associated with osteobiologic materials used in spinal fusion are well understood and clearly documented whereas others require further study and clarification. In any given clinical situation, the patient and surgeon need to balance the benefits and performance characteristics of the graft material with the risk profile to optimize clinical management.
基于文献的主题回顾。
回顾与脊柱融合常用的所有骨生物制剂相关的并发症和关注点。
在许多腰椎手术中，获得可靠的融合是一个重要目标，可使用多种骨移植物材料来实现这一目标。骼嵴骨移植物以及所有可用的骨生物替代物，对患者和外科医生都存在潜在的风险和担忧。
文献回顾和专家意见。
与脊柱融合中使用的骨生物材料相关的一些潜在并发症已经得到充分理解和明确记录，而其他并发症则需要进一步研究和澄清。在任何特定的临床情况下，患者和外科医生需要平衡移植物材料的益处和性能特点与风险状况，以优化临床管理。
