Dinter D J, Weidner A M, Wenz F, Pelzer A E, Michel M S, Schoenberg S O
Institut für Klinische Radiologie und Nuklearmedizin, Universitätsmedizin Mannheim, Medizinische Fakultät Mannheim der Universität Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Deutschland.
Urologe A. 2010 Aug;49(8):963-75. doi: 10.1007/s00120-010-2338-0.
Prostate cancer is the most common malignancy of men with approximately 32,000 new cases of prostate cancer in Germany and approximately 11,000 men who would die of the disease each year. For early diagnosis of prostate cancer PSA testing is used, whereas at present screening cannot be recommended due to the lack of confirmed medical and economic benefits. Regarding the imaging modalities, ultrasound of the prostate, currently performed in combination with elastography and histoscanning, magnetic resonance imaging of the prostate in combination with endorectal coils and positron emission tomography combined with computed tomography (PET-CT) are the methods of choice. Using these methods benign prostatitis can be differentiated from prostate cancer and staging of the tumor can be accomplished. On the other hand using these imaging methods it is possible to define the dominant intraprostatic lesion with different sensitivities and specificities, which is important for minimally invasive therapeutic strategies.
前列腺癌是男性中最常见的恶性肿瘤，在德国每年约有32000例前列腺癌新发病例，每年约有11000名男性死于该病。前列腺癌的早期诊断采用PSA检测，而目前由于缺乏确凿的医学和经济效益，不建议进行筛查。关于成像方式，目前结合弹性成像和组织扫描进行的前列腺超声检查、结合直肠内线圈的前列腺磁共振成像以及结合计算机断层扫描的正电子发射断层扫描（PET-CT）是首选方法。使用这些方法可以将良性前列腺炎与前列腺癌区分开来，并完成肿瘤分期。另一方面，使用这些成像方法可以以不同的敏感性和特异性确定前列腺内的主要病变，这对于微创治疗策略很重要。
