Durden Frederick L, Moore Charles E, Muller Susan
Department of Otolaryngology-Head and Neck Surgery, Emory University School of Medicine, Atlanta, GA 30322, USA.
Ear Nose Throat J. 2010 Jul;89(7):E21-3. doi: 10.1177/014556131008900704.
Verrucous carcinoma is a low-grade variant of squamous cell carcinoma reported to occur in all anatomic sites in the head and neck region, most commonly the oral cavity. The tumor grows locally invasive but is histologically benign and metastasizes rarely. To date, 22 cases of verrucous carcinoma involving the nasal cavity and/or the paranasal sinuses have been reported. We present a case of verrucous carcinoma involving the paranasal sinuses, nasal cavity, cranium, and orbit. This case highlights the difficulty of pathologic diagnosis and management options for a rare neoplastic lesion.
疣状癌是鳞状细胞癌的一种低级别变体，据报道可发生于头颈部区域的所有解剖部位，最常见于口腔。该肿瘤呈局部浸润性生长，但组织学上为良性，很少发生转移。迄今为止，已报道了22例累及鼻腔和/或鼻窦的疣状癌病例。我们报告一例累及鼻窦、鼻腔、颅骨和眼眶的疣状癌病例。该病例凸显了罕见肿瘤性病变的病理诊断及处理方案的困难之处。
