复发性指状黏液纤维瘤：75 例分析。

Recurrent digital glomus tumor: analysis of 75 cases.

机构信息

Department of Dermatology, Mackay Memorial Hospital, Taipei, Taiwan.

出版信息

Dermatol Surg. 2010 Sep;36(9):1396-400. doi: 10.1111/j.1524-4725.2010.01647.x. Epub 2010 Jul 9.

DOI:10.1111/j.1524-4725.2010.01647.x

PMID:20629689

Abstract

BACKGROUND

Glomus tumors are rare, benign, cutaneous neoplasms that must be excised completely to prevent recurrence.

OBJECTIVE

To investigate factors associated with recurrence of glomus tumors after surgery.

METHODS AND MATERIALS

Fifty-eight women and 17 men with digital glomus tumors underwent surgery between 1990 and 2008 at our hospital. These cases were retrospectively analyzed. RESULTS Mean age at diagnosis was 41.8, with an average diagnostic delay of 3.9 years. The tumor was located on a finger in 70 cases (right, 29; left, 41) and a toe in five (right, 3; left, 2). The tumor recurred in 13 (17%) patients. Recurrence was more likely if the tumor was skin-colored (odds ratio (OR)=31.67, 95% confidence interval (CI)=2.68-373.74, p=.006) or located within the nail matrix (OR=5.79, 95% CI=1.03-32.49, p=.046). No recurrence occurred in patients who had had preoperative magnetic resonance imaging or ultrasound studies.

CONCLUSION

Skin-colored tumors or those in the nail matrix are at higher risk of recurrence. The authors have indicated no significant interest with commercial supporters.

摘要

背景

血管球瘤是一种罕见的良性皮肤肿瘤，必须完全切除以防止复发。

目的

探讨影响血管球瘤术后复发的相关因素。

方法和材料

1990 年至 2008 年间，我院对 58 名女性和 17 名男性手部血管球瘤患者进行了手术治疗。对这些病例进行了回顾性分析。

结果

诊断时的平均年龄为 41.8 岁，平均诊断延迟 3.9 年。肿瘤位于手指 70 例（右侧 29 例，左侧 41 例），脚趾 5 例（右侧 3 例，左侧 2 例）。13 例（17%）患者肿瘤复发。如果肿瘤呈肤色（比值比[OR]=31.67，95%置信区间[CI]=2.68-373.74，p=.006）或位于甲母质内（OR=5.79，95% CI=1.03-32.49，p=.046），则肿瘤更有可能复发。在接受术前磁共振成像或超声检查的患者中未发生复发。