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一种用于甲下血管球瘤切除的显微经甲手术入路。

A microscopic transungual surgical approach for subungual glomus tumor resection.

作者信息

Zhong Jianbo, Ali Kamran, Yang Ping, Zhao Xingyun, Xu Lou Inmaculada, Wu Liming

机构信息

Department of Dermatology, Zhejiang Chinese Medical University, Zhejiang, China.

Department of Dermatology, Affiliated Hangzhou First People's Hospital, School of Medicine, Westlake University, Zhejiang, China.

出版信息

Front Med (Lausanne). 2025 Aug 14;12:1607299. doi: 10.3389/fmed.2025.1607299. eCollection 2025.

Abstract

BACKGROUND

Glomus tumors, rare benign neoplasms developing from the glomus, often pose challenges in early detection due to their small size and subtle symptoms. Surgical removal remains the only primary treatment; however, existing approaches have limitations, particularly in preserving nail structure and minimizing recurrence rates. This study introduces the Microscopic Transungual Surgical Approach to overcome the drawbacks of existing procedures for glomus tumor excision and evaluate its efficacy in treating these tumors.

METHODS

We retrospectively analyzed 61 patients diagnosed with and treated for glomus tumors between 2014 and 2024, examining their clinical characteristics, diagnostic test results (Love's and Hildreth's tests), and MRI findings. The surgical approach included complete nail plate removal followed by microscopic tumor excision and attentive postoperative management.

RESULTS

The study included 61 glomus tumor patients [49 females (80.3%), 12 males (19.7%)] with a median age of 39 years. Tumors most commonly affected the thumb (39.3%) and ring finger (23.0%). Key clinical features included severe pain (98.4%), positive Love test (95.1%), and cold sensitivity (88.5%). Associated findings included nail deformities (50.8%) and bone changes (39.3%). At 1-year follow-up, 80.2% achieved satisfactory nail recovery, with a 4.9% recurrence rate.

CONCLUSION

Our study suggests the potential efficacy of the Microscopic Transungual Surgical Approach in treating glomus tumors. Its enhanced visualization contributes to complete removal of tumors with less surrounding tissue damage to lower recurrence rates and improved patient outcomes.

摘要

背景

血管球瘤是一种罕见的起源于血管球的良性肿瘤,由于其体积小且症状不明显,早期检测往往具有挑战性。手术切除仍然是唯一的主要治疗方法;然而,现有方法存在局限性,特别是在保留指甲结构和降低复发率方面。本研究引入了经甲显微镜手术方法,以克服现有血管球瘤切除手术的缺点,并评估其治疗这些肿瘤的疗效。

方法

我们回顾性分析了2014年至2024年间61例诊断为血管球瘤并接受治疗的患者,检查了他们的临床特征、诊断测试结果(洛夫氏和希尔德雷思氏试验)以及MRI表现。手术方法包括完全去除指甲板,然后进行显微镜下肿瘤切除和精心的术后管理。

结果

该研究纳入了61例血管球瘤患者[49例女性(80.3%),12例男性(19.7%)],中位年龄为39岁。肿瘤最常累及拇指(39.3%)和无名指(23.0%)。关键临床特征包括严重疼痛(98.4%)、洛夫氏试验阳性(95.1%)和冷敏感(88.5%)。相关表现包括指甲畸形(50.8%)和骨质改变(39.3%)。在1年的随访中,80.2%的患者指甲恢复满意,复发率为4.9%。

结论

我们的研究表明经甲显微镜手术方法在治疗血管球瘤方面具有潜在疗效。其增强的可视化有助于完全切除肿瘤,减少周围组织损伤,从而降低复发率并改善患者预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d03f/12392112/1da3371b76d7/fmed-12-1607299-g001.jpg

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