Labauge R, Pagès M, Vastène M, Blard J M
Clinique Neurologique, Montpellier.
Rev Neurol (Paris). 1991;147(3):208-14.
Twenty-three cases of vertebro-basilar aneurysms observed in a neurology department are reported. Ten were located on the basilar artery (7 at the basilar bifurcation), 5 on the postero-inferior cerebellar arteries, 4 on the superior cerebellar arteries, 3 on the vertebro-basilar junction and 1 on the anteroinferior cerebellar artery. There were 6 fusiform and giant aneurysms, others were sacciform. In 5 cases, there was no clear relationship between the clinical data and the aneurysm, which was discovered by chance at angiography or MRI. One giant aneurysm of the basilar artery was mimicking a tumor of the posterior cerebral fossa. Two other cases were revealed by brain stem ischaemia. Aneurysmal rupture was present in 15 cases: there were signs of meningeal haemorrhage in all cases and clinical signs of posterior cerebral fossa involvement in 7 cases. CT scan, performed in 8 cases, showed in all of them a meningeal haemorrhage, with a brain stem haematoma in 3 cases. All the aneurysms were shown by angiography; 7 were associated with a vasospasm. Five patients were not operated upon; all died. In one case, clipping the aneurysm was impossible, but there was a good recovery with a 12 year follow-up. Nine patients were operated, 3 recovered completely, 2 had neurological sequelae, 1 a late worsening; 3 patients died of brain stem ischaemia.
本文报告了某神经内科观察到的23例椎基底动脉瘤病例。其中10例位于基底动脉(7例位于基底动脉分叉处),5例位于小脑后下动脉,4例位于小脑上动脉,3例位于椎基底动脉交界处,1例位于小脑前下动脉。有6例为梭形和巨大动脉瘤,其余为囊状动脉瘤。5例患者的临床资料与动脉瘤之间无明确关联,这些动脉瘤是在血管造影或磁共振成像(MRI)检查时偶然发现的。1例基底动脉巨大动脉瘤类似后颅窝肿瘤。另外2例由脑干缺血发现。15例出现动脉瘤破裂:所有病例均有脑膜出血体征,7例有后颅窝受累的临床体征。8例行CT扫描,均显示脑膜出血,3例有脑干血肿。所有动脉瘤均经血管造影显示;7例伴有血管痉挛。5例患者未接受手术治疗,均死亡。1例无法夹闭动脉瘤,但随访12年恢复良好。9例患者接受手术,3例完全康复,2例有神经后遗症,1例病情后期恶化;3例患者死于脑干缺血。