Labauge R, Pagès M, Tourniaire D, Favier J P, Blard J M
Clinique Neurologique, Montpellier.
Rev Neurol (Paris). 1991;147(4):317-9.
A 28-years old woman, working as a secretary, developed a rapidly progressive paraplegia with burning pain in the lower limbs. She recovered within 4 months but relapsed shortly after she was discharged. There was flaccid tetraplegia, associated with hyperalgesia of the limbs, diffuse muscle atrophy, blindness and alopecia. The patient needed respiratory assistance for 2 months. Bilateral optic neuropathy and paraparesis persisted after a 17 months follow-up. The clinical picture suggested thallium poisoning, which was confirmed by high thallium concentration in plasma and urine. The most likely cause was accidental poisoning with rodenticides.
一名28岁的女性秘书，出现了迅速进展的截瘫，并伴有下肢灼痛。她在4个月内康复，但出院后不久复发。出现弛缓性四肢瘫，伴有肢体痛觉过敏、弥漫性肌肉萎缩、失明和脱发。患者需要2个月的呼吸支持。经过17个月的随访，双侧视神经病变和轻截瘫持续存在。临床表现提示铊中毒，血浆和尿液中高铊浓度证实了这一点。最可能的原因是意外接触杀鼠剂中毒。
