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[铊中毒所致复发性周围神经病]

[Recurrent peripheral neuropathy caused by thallium poisoning].

作者信息

Labauge R, Pagès M, Tourniaire D, Favier J P, Blard J M

机构信息

Clinique Neurologique, Montpellier.

出版信息

Rev Neurol (Paris). 1991;147(4):317-9.

PMID:2063083
Abstract

A 28-years old woman, working as a secretary, developed a rapidly progressive paraplegia with burning pain in the lower limbs. She recovered within 4 months but relapsed shortly after she was discharged. There was flaccid tetraplegia, associated with hyperalgesia of the limbs, diffuse muscle atrophy, blindness and alopecia. The patient needed respiratory assistance for 2 months. Bilateral optic neuropathy and paraparesis persisted after a 17 months follow-up. The clinical picture suggested thallium poisoning, which was confirmed by high thallium concentration in plasma and urine. The most likely cause was accidental poisoning with rodenticides.

摘要

一名28岁的女性秘书,出现了迅速进展的截瘫,并伴有下肢灼痛。她在4个月内康复,但出院后不久复发。出现弛缓性四肢瘫,伴有肢体痛觉过敏、弥漫性肌肉萎缩、失明和脱发。患者需要2个月的呼吸支持。经过17个月的随访,双侧视神经病变和轻截瘫持续存在。临床表现提示铊中毒,血浆和尿液中高铊浓度证实了这一点。最可能的原因是意外接触杀鼠剂中毒。

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