Clínica de Osteoporosis, Hospital Aranda de Parra, Hidalgo 329-704, León, 37000 GTO, México.
Clin Rheumatol. 2010 Oct;29(10):1085-91. doi: 10.1007/s10067-010-1489-0. Epub 2010 Jul 15.
Osteoporosis is a generalized disease of bone that increases fracture risk. Multiple factors influence this risk, besides low bone mass. To decrease osteoporotic fractures, those patients who require preventive management should be readily identified. This paper aims to review current information on the use of the fracture risk assessment tool (FRAX) in Latin America. Bone mineral density measurement is currently the method of reference for evaluating the fracture risk and opting for treatment; but, it misses a notable proportion of individuals who have clinical risk factors for osteoporosis and fractures. FRAX was designed to predict the 10-year absolute risk of sustaining a major osteoporotic fracture or a hip fracture. Although data is available for several countries, from Latin America, only Argentina appears in the current version of the tool. Its present use in other Latin American countries is possible with some adaptations based in similarities of epidemiological information of each country with some of the existing databases. The cutoff value beyond which treatment should be initiated needs to be determined, based not only on clinical criteria, but also on economic considerations.
骨质疏松症是一种全身性骨骼疾病，会增加骨折风险。除了骨量低之外，还有多种因素会影响这种风险。为了减少骨质疏松性骨折，应该能够轻易识别出需要预防管理的患者。本文旨在综述目前在拉丁美洲使用骨折风险评估工具（FRAX）的信息。骨密度测量目前是评估骨折风险和选择治疗方法的参考方法；但是，它忽略了相当一部分存在骨质疏松症和骨折临床风险因素的个体。FRAX 旨在预测 10 年内发生主要骨质疏松性骨折或髋部骨折的绝对风险。尽管该工具在多个国家都有数据，但来自拉丁美洲的国家中，只有阿根廷出现在当前版本中。根据每个国家与现有数据库中的一些数据库的流行病学信息相似性，进行一些调整，在其他拉丁美洲国家也可以使用该工具。起始治疗的截止值不仅需要基于临床标准，还需要基于经济考虑来确定。
