David R, Buchner A
Cancer. 1978 May;41(5):1836-44. doi: 10.1002/1097-0142(197805)41:5<1836::aid-cncr2820410527>3.0.co;2-3.
Amyloid as defined by positive Congo red green birefringence and STB red birefringence was observed in the stroma of a tubular carcinoma of minor salivary gland origin. The amyloid exhibited additional histochemical characteristics of immunamyloid, viz., positive DMAB-nitrate and DC-reactions and spontaneous autofluorescence. Electron microscopic studies of the epithelial tumor cells displayed large amounts of cytoplasmic microfilaments similar to those present in the extracellular amyloid masses. It is suggested that the amyloid is derived from spontaneous assembly or polymerization of cytoplasmic microfibrils of the dying tumor cells as has been proposed for the amyloid associated with the calcifying epithelial odontogenic tumor (CEOT).
经刚果红阳性绿色双折射和硫黄素T红色双折射定义的淀粉样物质，在起源于小唾液腺的管状癌基质中被观察到。该淀粉样物质表现出免疫淀粉样物质的其他组织化学特征，即二甲基甲酰胺-硝酸盐阳性和二氯荧光素反应阳性以及自发自体荧光。上皮肿瘤细胞的电子显微镜研究显示，大量细胞质微丝与细胞外淀粉样物质团块中的微丝相似。有人提出，与钙化上皮性牙源性肿瘤（CEOT）相关的淀粉样物质是由垂死肿瘤细胞的细胞质微原纤维自发组装或聚合形成的，本文认为该淀粉样物质也是如此。
