Vinson David R, Hoehn Ted, Graber David J, Williams Terry M
The Permanente Medical Group, Kaiser Permanente Roseville Medical Center, Roseville, California, USA.
J Emerg Med. 2012 Feb;42(2):139-48. doi: 10.1016/j.jemermed.2010.05.017. Epub 2010 Jul 15.
The management of emergency department (ED) patients with presumed recent-onset atrial fibrillation or flutter≤48h in duration varies widely.
We conducted a prospective study across three affiliated community EDs within a large integrated health care delivery system to describe the management of patients with recent-onset atrial fibrillation or flutter, to determine the safety and effectiveness of ED cardioversion, and to measure the incidence of thromboembolism 30 days after discharge.
We enrolled 206 patients with convenience sampling between June 2005 and November 2007. Mean age was 64.0±14.4 years (range 21-96 years). Patients were grouped for analysis into four categories based on whether cardioversion was 1) spontaneous in the ED (59; 28.6%); 2) attempted with electrical or pharmacological means (115; 56.3%), with success in 110 (95.7%); 3) hoped for during a short stint of home observation (16; 7.8%, 11 of which spontaneously converted to sinus rhythm within 24h); or 4) contraindicated (16; 7.8%). Of the entire group, 183 (88.8%) patients were discharged home. Adverse events requiring ED interventions were reported in 6 (2.9%; 95% confidence interval [CI] 1.1-6.2%) patients, all of whom recovered. Two (1.0%; 95% CI 0.1-3.5%) patients were found to have an embolic event on 30-day follow-up.
Our approach to ED patients with presumed recent-onset atrial fibrillation or flutter seems to be safe and effective, with a high rate of cardioversion and discharge to home coupled with a low ED adverse event and 30-day thromboembolic event rate.
对于急诊科(ED)中发病时间推测在48小时以内的房颤或房扑患者,其治疗方法差异很大。
我们在一个大型综合医疗服务系统内的三家附属医院急诊科开展了一项前瞻性研究,以描述近期发病的房颤或房扑患者的治疗情况,确定急诊科心脏复律的安全性和有效性,并测量出院后30天内血栓栓塞的发生率。
我们在2005年6月至2007年11月期间采用方便抽样法纳入了206例患者。平均年龄为64.0±14.4岁(范围21 - 96岁)。根据心脏复律情况,患者被分为四类进行分析:1)在急诊科自行转复(59例;28.6%);2)尝试采用电或药物方法复律(115例;56.3%),其中110例成功(95.7%);3)希望在短期家庭观察期间转复(16例;7.8%),其中11例在24小时内自行转为窦性心律;或4)禁忌复律(16例;7.8%)。在整个研究组中,183例(88.8%)患者出院回家。有6例(2.9%;95%置信区间[CI] 1.1 - 6.2%)患者报告了需要急诊科干预的不良事件,所有患者均康复。在30天随访中发现2例(1.0%;95% CI 0.1 - 3.5%)患者发生栓塞事件。
我们对急诊科中推测近期发病的房颤或房扑患者的治疗方法似乎是安全有效的,心脏复律率和出院回家率高,同时急诊科不良事件和30天血栓栓塞事件发生率低。