Pavicić-Astalos Jasna, Iveković Renata, Knezević Tamara, Krolo Iva, Novak-Laus Katia, Tedeschi-Reiner Eugenia, Rotim Kresimir, Mandić Kresimir, Susić Nikola
University Department of Ophthalmology, Sestre milosrdnice University Hospital, Zagreb, Croatia.
Acta Clin Croat. 2010 Mar;49(1):43-8.
The aim of the study was to evaluate the efficacy of intralesional triamcinolone acetonide injection in primary and recurrent chalazion. The study included 30 patients with primary and recurrent chalazion (37 cases) and 24 patients as a control group. Patients with primary and recurrent chalazion received intralesional injection of 0.1 to 0.2 mL triamcinolone acetonide (40 mg/mL). Control group received intralesional injection of 0.1 to 0.2 mL 0.9% NaCl. Data on the lesion size, including digital color photography, lesion regression or recurrence, and complete ophthalmic examination were recorded at the time of injection and after a week or two until resolution or surgical excision. Success was defined as at least 80% decrease in size with no recurrence. Resolution of the lesion was found in 35 cases after one or two injections, with a mean time to resolution of 15.27 +/- 6.12 days. Subcutaneous injection of the steroid triamcinolone acetonide in primary and recurrent chalazion appears to be a simple and efficacious therapeutic option for chalazion.
本研究的目的是评估病灶内注射曲安奈德治疗原发性和复发性睑板腺囊肿的疗效。该研究纳入了30例原发性和复发性睑板腺囊肿患者（37例），并将24例患者作为对照组。原发性和复发性睑板腺囊肿患者接受病灶内注射0.1至0.2 mL曲安奈德（40 mg/mL）。对照组接受病灶内注射0.1至0.2 mL 0.9%氯化钠溶液。在注射时以及注射后一两周直至病灶消退或手术切除，记录病灶大小的数据，包括数码彩色照片、病灶消退或复发情况以及完整的眼科检查。成功定义为病灶大小至少减少80%且无复发。一两次注射后，35例患者的病灶消退，平均消退时间为15.27 +/- 6.12天。皮下注射类固醇曲安奈德治疗原发性和复发性睑板腺囊肿似乎是一种简单有效的治疗选择。
