Romanova A F, Fedorovskaia E A, Pesotskaia L A
Vrach Delo. 1991 Apr(4):65-7.
Twenty patients with chronic myeloleucosis in the stage of blast crisis were examined. Results of immunological investigations indicate that these patients showed below normal indices of the absorptive and bactericidal function of polymorphous-nuclear neutrophils and cationic proteins. The number of T- and B-lymphocytes was also reduced. The immunity values were to the same degree inhibited as in patients with acute leucosis. Changes of the immune status depend on the degree of blastemia. Along with cytostatic agents patients with chronic myeloleucosis in the stage of blast crisis should undergo immunocorrection, primarily correction of cellular immunity.
对20例处于原始细胞危象期的慢性粒细胞白血病患者进行了检查。免疫学研究结果表明，这些患者的多形核中性粒细胞的吸收和杀菌功能以及阳离子蛋白指标低于正常水平。T淋巴细胞和B淋巴细胞的数量也减少了。免疫值受到的抑制程度与急性白血病患者相同。免疫状态的变化取决于原始细胞血症的程度。除细胞抑制剂外，处于原始细胞危象期的慢性粒细胞白血病患者应进行免疫纠正，主要是细胞免疫的纠正。
