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有指征性宫颈环扎术史的孕妇,宫颈环扎术高度与早产发生率是否相关?

Is cerclage height associated with the incidence of preterm birth in women with a history-indicated cerclage?

机构信息

Department of Obstetrics and Gynecology, Lankenau Hospital, Wynnewood, Pennsylvania, USA.

出版信息

Am J Perinatol. 2011 Jan;28(1):83-6. doi: 10.1055/s-0030-1262908. Epub 2010 Jul 16.

DOI:10.1055/s-0030-1262908
PMID:20640973
Abstract

This study was performed to determine if cerclage height is associated with spontaneous preterm birth in patients with a history-indicated cerclage. We performed a retrospective cohort study of women with a history-indicated cerclage. Functional cervical length and the cerclage height (distance from cerclage to the external cervical os) were obtained. The cohort was grouped into thirds, based on cerclage height percentile. Our primary outcome was spontaneous preterm birth <35 weeks. There were 21 women in group 1 (cerclage height <10 mm), 53 in group 2 (cerclage height 10 to 19 mm), and 31 in group 3 (cerclage height ≥20 mm). The rates of spontaneous preterm birth <35 weeks were similar between each group: 24, 17, and 10%, respectively ( P = 0.38). Cerclage height is not associated with a reduction in spontaneous preterm birth for women with a history-indicated cerclage. The association between longer cerclage height and decrease in preterm birth was nonsignificant possibly due to the small sample size.

摘要

这项研究旨在确定对于有指征行宫颈环扎术病史的患者,宫颈环扎高度是否与自发性早产有关。我们对有指征行宫颈环扎术病史的女性进行了回顾性队列研究。获得了功能宫颈长度和宫颈环扎高度(从宫颈环扎到宫颈外口的距离)。根据宫颈环扎高度的百分位数,将队列分为三组。我们的主要结局是自发性早产<35 周。第 1 组有 21 名女性(宫颈环扎高度<10 毫米),第 2 组有 53 名女性(宫颈环扎高度 10 至 19 毫米),第 3 组有 31 名女性(宫颈环扎高度≥20 毫米)。三组自发性早产<35 周的发生率相似:分别为 24%、17%和 10%(P=0.38)。对于有指征行宫颈环扎术病史的女性,宫颈环扎高度与自发性早产减少无关。宫颈环扎高度与早产减少之间的关联无统计学意义,可能是由于样本量小。

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