蛇毒凝血障碍：蝰蛇科毒蛇咬伤治疗中血液制品的使用与滥用

Snake venom coagulopathy: use and abuse of blood products in the treatment of pit viper envenomation.

作者信息

Burgess J L, Dart R C

机构信息

Section of Emergency Medicine, University of Arizona, Tucson 85724.

出版信息

Ann Emerg Med. 1991 Jul;20(7):795-801. doi: 10.1016/s0196-0644(05)80845-5.

DOI:10.1016/s0196-0644(05)80845-5

PMID:2064103

Abstract

Coagulopathies are commonly encountered in victims of pit viper envenomation. In the majority of patients these defects improve with administration of antivenin. However, blood products are often transfused based on arbitrary criteria and with significant risk to the patient. This article documents the effectiveness and risks of antivenin administration and the risks of blood product transfusion. We recommend that blood products not be used except for clearly defined clinical indications.

摘要

凝血障碍在蝰蛇咬伤患者中很常见。在大多数患者中，这些凝血缺陷通过注射抗蛇毒血清得以改善。然而，血液制品常根据随意的标准进行输注，给患者带来很大风险。本文记录了注射抗蛇毒血清的有效性和风险以及输注血液制品的风险。我们建议，除非有明确界定的临床指征，否则不应使用血液制品。