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Cheyne-Stokes respiration in patients with cardiac enlargement and prolonged circulation time.心脏扩大和循环时间延长患者的潮式呼吸。
Circulation. 1951 Aug;4(2):233-8. doi: 10.1161/01.cir.4.2.233.
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Sleep apnea and heart failure: Part II: central sleep apnea.睡眠呼吸暂停与心力衰竭：第二部分：中枢性睡眠呼吸暂停
Circulation. 2003 Apr 8;107(13):1822-6. doi: 10.1161/01.CIR.0000061758.05044.64.
4
Relation between oscillatory ventilation at rest before cardiopulmonary exercise testing and prognosis in patients with left ventricular dysfunction.左心室功能障碍患者心肺运动试验前静息时振荡通气与预后的关系。
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Am J Cardiol. 1998 Feb 15;81(4):432-6. doi: 10.1016/s0002-9149(97)00936-3.
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Central sleep apnea-hypopnea syndrome in heart failure: prevalence, impact, and treatment.心力衰竭中的中枢性睡眠呼吸暂停低通气综合征：患病率、影响及治疗
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8
Increased mortality associated with Cheyne-Stokes respiration in patients with congestive heart failure.充血性心力衰竭患者中与潮式呼吸相关的死亡率增加。
Am J Respir Crit Care Med. 1996 Jan;153(1):272-6. doi: 10.1164/ajrccm.153.1.8542128.
9
Mechanism of periodic breathing in patients with cardiovascular disease.心血管疾病患者周期性呼吸的机制。
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10
Oscillatory hyperventilation in severe congestive heart failure secondary to idiopathic dilated cardiomyopathy or to ischemic cardiomyopathy.特发性扩张型心肌病或缺血性心肌病所致严重充血性心力衰竭中的振荡性过度通气。
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清醒振荡通气在心力衰竭患者中的临床意义及心脏直视手术的影响。

Clinical significance of awake oscillatory ventilation in patients with heart failure and effects of open-heart surgery.

机构信息

EBM Research Center, Kyoto University Graduate School of Medicine, Kyoto, Japan. k

出版信息

Clin Cardiol. 2010 Jul;33(7):E20-3. doi: 10.1002/clc.20572.

DOI:10.1002/clc.20572
PMID:20641105
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6653024/
Abstract

BACKGROUND

Although sleep apnea has recently become a concern in patients with congestive heart failure (CHF), some patients with CHF exhibit characteristic oscillatory ventilation (OV) even when they are awake. We investigated the clinical significance of OV in patients with CHF, and effects of open-heart surgery on the OV.

HYPOTHESIS

OV is an indicator of the severity of CHF, and this abnormal respiratory pattern improves with hemodynamic changes after open-heart surgery.

METHODS

According to respiratory pattern in the cardiopulmonary exercise testing (CPX) before cardiac surgery, 50 patients with CHF were divided into 14 patients of OV-positive (OV+) and 36 patients of OV-negative (OV-). Then, the several indices of CPX before surgery, 1 week and 6 months after surgery were compared between the 2 groups.

RESULTS

The peak VO2 before surgery was lower in OV+ patients than those in OV- patients (15.3 vs 18.8 m1/min/kg, p < 0.05). One week after surgery, anaerobic threshold (AT) and end-tidal C02 (ETC02) were lower in OV+ patients than those in OV- patients (AT: 9.5 vs 10,7 ml/min/kg, p < 0.05, ETCO2: 5.3 vs 5.6%, p < 0.05). However, 6 months after surgery, the statistical differences of these CPX parameters between the 2 groups were not found, and OV disappeared in 79% of OV+ patients.

CONCLUSIONS

These data suggest that OV is an indicator of the severity of CHF, and gradually improved with the open-heart surgery.

摘要

背景

尽管睡眠呼吸暂停症最近成为充血性心力衰竭（CHF）患者关注的焦点，但一些 CHF 患者即使在清醒时也会表现出特征性的振荡性通气（OV）。我们研究了 CHF 患者 OV 的临床意义，以及心脏直视手术后对 OV 的影响。

假说

OV 是 CHF 严重程度的一个指标，这种异常呼吸模式在心脏直视手术后随着血液动力学变化而改善。

方法

根据心脏手术前心肺运动测试（CPX）中的呼吸模式，将 50 例 CHF 患者分为 OV 阳性（OV+）组 14 例和 OV 阴性（OV-）组 36 例。然后，比较两组患者术前、术后 1 周和 6 个月的 CPX 多项指标。

结果

OV+患者术前峰值 VO2 低于 OV-患者（15.3 比 18.8ml/min/kg，p<0.05）。术后 1 周，OV+患者的无氧阈值（AT）和呼气末 CO2（ETC02）低于 OV-患者（AT：9.5 比 10.7ml/min/kg，p<0.05，ETCO2：5.3 比 5.6%，p<0.05）。然而，术后 6 个月，两组间 CPX 各项参数的差异均无统计学意义，OV+患者中有 79%的患者 OV 消失。

结论

这些数据表明，OV 是 CHF 严重程度的一个指标，并且随着心脏直视手术而逐渐改善。