Dermatology Department, University Hospital of Coimbra, Portugal.
J Cutan Med Surg. 2010 Jul-Aug;14(4):175-7. doi: 10.2310/7750.2010.09028.
scabies is a common infestation that usually presents as a pruriginous eruption consisting of erythematous papules, nodules, and excoriations. Diagnosis relies mostly on clinical features, including the identification of scabietic burrows. Several atypical clinical manifestations have been reported; bullous presentations are particularly rare and intriguing.
a case of recurrent bullous scabies is reported.
an 87-year-old institutionalized woman developed a pruriginous eruption that mimicked bullous pemphigoid. Histopathologic examination revealed blistering at the subepidermal level and a mixed inflammatory infiltrate with numerous eosinophils. Scabies mites were identified on dermoscopy and on skin scrapings, allowing a diagnosis of bullous scabies. Despite effective treatment with topical lindane, failure to control scabies in her institution led to recurrences of her peculiar blistering infestation. Immunofluorescence studies were always negative.
these observations underscore the mite's role in the pathogenesis of blister formation and illustrate current challenges in scabies' diagnosis and management.
疥疮是一种常见的寄生虫感染,通常表现为瘙痒性皮疹,包括红斑丘疹、结节和抓痕。诊断主要依赖于临床特征,包括疥螨隧道的识别。已经报道了几种不典型的临床表现;水疱表现尤其罕见且有趣。
报告一例复发性水疱性疥疮。
一名 87 岁的住院女性患者出现了类似于大疱性类天疱疮的瘙痒性皮疹。组织病理学检查显示表皮下水疱形成和混合性炎症浸润,其中有大量嗜酸性粒细胞。在皮镜和皮肤刮片中发现了疥螨,从而确诊为水疱性疥疮。尽管使用林丹进行了有效的局部治疗,但由于未能在医疗机构中控制疥疮,导致她的水疱性感染反复发作。免疫荧光研究始终为阴性。
这些观察结果强调了螨虫在水疱形成发病机制中的作用,并说明了当前在疥疮诊断和管理方面的挑战。