Dermatology and Pathology Units, University of Padua, Padua, Italy.
J Cutan Med Surg. 2011 Jan-Feb;15(1):55-7. doi: 10.2310/7750.2011.10040.
Scabies is a contagious infestation affecting subjects of all ages, races, and social conditions.
We report a case of a 79-year-old man who developed a bullous pemphigoid-like eruption. He presented to our unit 4 months after the onset of symptoms. An autoimmune bullous disease was suspected. Direct immunofluorescence on a skin specimen and anti-desmoglein 1, anti-desmoglein 3, and anti-bullous pemphigoid antigen 180 were negative. Surprisingly, the histology of a skin lesion demonstrated the presence of scabies, which was successfully treated with benzyl benzoate 20%.
The diagnosis of bullous scabies should be considered for any bullous eruptions accompanied by papules and itching resistant to steroid treatment and with negative immunopathologic findings.
疥疮是一种传染性寄生虫病，影响所有年龄、种族和社会条件的人群。
我们报告了一例 79 岁男性，他出现了类大疱性类天疱疮样皮疹。他在症状出现后 4 个月到我们科室就诊。怀疑是自身免疫性大疱性疾病。皮肤标本的直接免疫荧光和抗桥粒芯糖蛋白 1、抗桥粒芯糖蛋白 3 和抗大疱性类天疱疮抗原 180 均为阴性。令人惊讶的是，皮肤病变的组织学显示存在疥疮，用 20%苯甲酸苄酯治疗后成功治愈。
对于任何伴有丘疹、瘙痒的大疱性皮疹，且类固醇治疗无效、免疫病理学检查结果为阴性，都应考虑大疱性疥疮的诊断。
