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酗酒导致有生命威胁的可逆转酸中毒。

Life-threatening reversible acidosis caused by alcohol abuse.

机构信息

Department of Nephrology & Hypertension, Kaplan Medical Center, Rehovot 76100, Israel.

出版信息

Nat Rev Nephrol. 2010 Sep;6(9):555-9. doi: 10.1038/nrneph.2010.99. Epub 2010 Jul 20.

Abstract

BACKGROUND

A 52-year-old man with a history of alcohol dependency was admitted to the emergency room with life-threatening anion gap metabolic acidosis. He admitted to drinking large quantities of alcohol during the previous day.

INVESTIGATIONS

Physical examination, blood and urine analyses, including calculation of his anion gap and plasma osmolal gap, and measurement of serum alcohol levels.

DIAGNOSIS

Severe but rapidly reversible lactic acidosis and associated alcohol-induced ketoacidosis.

MANAGEMENT

Intravenous thiamine, intravenous fluids and bicarbonate.

摘要

背景

一名 52 岁男性,有酒精依赖史,因危及生命的阴离子间隙代谢性酸中毒被收入急诊室。他承认前一天喝了大量的酒。

检查

体格检查、血液和尿液分析,包括计算阴离子间隙和血浆渗透压间隙,以及检测血清酒精水平。

诊断

严重但迅速可逆的乳酸性酸中毒和相关的酒精性酮症酸中毒。

治疗

静脉注射硫胺素、静脉补液和碳酸氢盐。

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