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用于治疗皮肤假性淋巴瘤的ALA-光动力疗法:一例报告

ALA-PDT for the treatment of cutaneous pseudolymphoma: a case report.

作者信息

O'Neill Jenna, Fien Sari, Zeitouni Nathalie C

机构信息

Department of Dermatology, State University of NewYork at Buffalo, Buffalo, NY, USA.

出版信息

J Drugs Dermatol. 2010 Jun;9(6):688-9.

Abstract

Cutaneous pseudolymphoma (CPL) is a benign skin condition that may cause cosmetic disfigurement, severe itch and, albeit rarely, transformation to malignant lymphoma. The usual treatment modalities for CPL have been associated with adverse effects including skin atrophy and scarring. This article reports the case of a patient with CPL on the cheek, which was treated with 5-aminolevulinic acid photodynamic therapy (ALA-PDT). Clinically significant improvement in lesion size and symptoms was noted, with few side effects. Controlled trials and long-term monitoring are warranted to further explore this treatment modality for CPL.

摘要

皮肤假性淋巴瘤(CPL)是一种良性皮肤疾病,可能导致外观毁损、剧烈瘙痒,尽管罕见,但也可能转变为恶性淋巴瘤。CPL的常规治疗方式会带来包括皮肤萎缩和瘢痕形成等不良反应。本文报告了一例脸颊患有CPL的患者,采用5-氨基酮戊酸光动力疗法(ALA-PDT)进行治疗。结果显示皮损大小和症状有显著临床改善,且副作用较少。有必要开展对照试验和长期监测,以进一步探索CPL的这种治疗方式。

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