Pavicic Tatjana, Ruzicka Thomas, Korting Hans-Christian, Gauglitz Gerd
Department of Dermatology, Ludwig-Maximillians-University, Munich, Germany.
J Drugs Dermatol. 2010 Jun;9(6):690-5.
Human immunodeficiency virus (HIV)-associated facial lipoatrophy (FLA) represents a common and highly stigmatizing side effect of retroviral therapy. By causing loss of subcutaneous adipose tissue mainly in the cheek, temple and periocular area, FLA can significantly affect the patient's quality of life, both physically and psychologically. A limited quantity of data has been published on various filling substances for the management of FLA. Here, the authors present two patients with HIV-associated FLA successfully treated with a novel HA filler over a period of 24 months.
人类免疫缺陷病毒（HIV）相关面部脂肪萎缩（FLA）是逆转录病毒治疗常见且极具 stigmatizing 的副作用。FLA 主要导致脸颊、颞部和眼周皮下脂肪组织流失，会在生理和心理上显著影响患者的生活质量。关于用于治疗 FLA 的各种填充物质的已发表数据有限。在此，作者介绍了两名 HIV 相关 FLA 患者，在 24 个月的时间里成功使用一种新型透明质酸（HA）填充剂进行了治疗。 （注：这里“stigmatizing”可能是“令人感到羞耻的、有污名化影响的”意思，但因要求不添加解释，保留英文未译）
