Sebag J
Doheny Eye Institute, University of Southern California, Los Angeles.
Arch Ophthalmol. 1991 Jul;109(7):966-71. doi: 10.1001/archopht.1991.01080070078039.
Age-related differences in vitreoretinal adhesion were investigated in 59 human eyes from donors aged from 33 weeks of gestation to 94 years with the use of dark-field and electron microscopy of whole vitreous. In all eyes from individuals aged 21 years or older, dissection of the retina off the vitreous resulted in cleavage between the vitreous cortex and the internal limiting lamina. However, in six (40%) of 15 eyes from individuals aged 20 years or younger, the internal limiting lamina remained adherent to the vitreous cortex in an area that encompassed the macula, temporal arcades, and peripapillary posterior pole. Ultrastructural studies revealed inner portions of Müller's cells that were attached to the posterior aspect of the internal limiting lamina. These results suggested that, in youth, there is adhesion between the vitreous cortex and internal limiting lamina that is stronger than Müller's cell itself and is topographically more extensive than previously thought.
利用全玻璃体暗视野和电子显微镜技术，对59只来自妊娠33周龄至94岁供体的人眼进行了玻璃体视网膜粘连的年龄相关性差异研究。在所有21岁及以上个体的眼睛中，视网膜与玻璃体分离导致玻璃体皮质与内界膜之间的劈裂。然而，在15只20岁及以下个体的眼睛中，有6只（40%）的内界膜在包括黄斑、颞侧血管弓和视乳头周围后极的区域仍与玻璃体皮质粘连。超微结构研究显示，米勒细胞的内部部分附着在内界膜的后部。这些结果表明，在年轻人中，玻璃体皮质与内界膜之间的粘连比米勒细胞本身更强，并且在地形上比以前认为的更广泛。
