Gurung Rajya L, Lake Stewart, Durkin Shane, Sia David, Gilhotra Jagjit, Chan Weng Onn
Department of Ophthalmology, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
Department of Ophthalmology, Flinders Medical Centre, Adelaide, South Australia, Australia.
Graefes Arch Clin Exp Ophthalmol. 2025 Jun 18. doi: 10.1007/s00417-025-06869-8.
The vitreous is a transparent homogenous gel comprised predominantly of water. It is firmly attached to the internal limiting membrane in young healthy individuals. As part of the physiological aging process, the separation of the posterior vitreous cortex from the internal limiting membrane is called physiological posterior vitreous detachment (PVD), which usually occurs without ocular complications. On the contrary, anomalous PVD can have various sight-threatening complications. The cause of this difference is poorly understood and is a topic of future research. Further, newer evidence indicates that anomalous PVD may be genetically influenced.
玻璃体是一种主要由水组成的透明均质凝胶。在年轻健康个体中，它与内界膜紧密相连。作为生理老化过程的一部分，玻璃体后皮质与内界膜的分离被称为生理性玻璃体后脱离（PVD），通常不会引发眼部并发症。相反，异常的PVD可能会引发各种威胁视力的并发症。这种差异的原因尚不清楚，是未来研究的一个课题。此外，最新证据表明，异常的PVD可能受遗传影响。
