Department of Chemistry, Faculty of Arts and Sciences, Karadeniz Technical University, Trabzon, Turkey.
Pharm Biol. 2010 Feb;48(2):191-4. doi: 10.3109/13880200903074627.
Chemical compositions of the essential oil of Sedum pallidum Bieb. var. bithynicum (Boiss.) and S. spurium Bieb. (Crassulaceae) from Turkey were investigated by GC-MS, and antimicrobial activity of the oil samples were assessed against Gram-positive/negative bacteria and yeast-like fungi. Thirty-eight and thirty-five components were identified in the essential oils and the main components of these species were found to be caryophyllene oxide from S. pallidum var. bithynicum and hexahydrofarnesyl acetone from S. spurium in the ratios of 12.8% and 15.7%, respectively. The isolated essential oils of the plants showed low antimicrobial activity against Gram-negative/positive bacteria and yeast-like fungi, having the MIC values of 500-2000 microg/mL. Antibacterial activity was not observed against Bacillus cereus.
采用 GC-MS 法分析了土耳其产Sedum pallidum Bieb. var. bithynicum（Boiss.）和 S. spurium Bieb.（景天科）的精油化学成分，并评估了油样对革兰氏阳性/阴性细菌和酵母样真菌的抗菌活性。在精油中鉴定出 38 种和 35 种成分，这两种植物的主要成分分别为石竹烯氧化物（12.8%）和六氢法呢基丙酮（15.7%）。植物中分离出的精油对革兰氏阴性/阳性细菌和酵母样真菌的抗菌活性较低，其 MIC 值为 500-2000μg/mL。对蜡样芽孢杆菌没有观察到抗菌活性。
