Huang Sheng-Li, Shi Wei, Zhang Li-Gen
Department of Neurosurgery, the Second Affiliated Hospital, School of Medicine, Xi'an Jiaotong University, Xi'an 710004, China.
Zhonghua Wai Ke Za Zhi. 2010 May 15;48(10):750-2.
To investigate the methods and techniques of surgical treatment of lipomyelomeningocele in children.
From January 2004 to March 2007, twenty-five children aged from 2 months to 6 years with lipomyelomeningocele were operated on. Magnetic resonance imaging and electromyogram had been conducted to all the patients. The operation was composed of subtotal excision of lipomas, suture of spinal pia mater and resection of terminal filum. The results of treatment were evaluated by Hoffman's functional grading scheme for lipomyelomeningocele.
After operation, all the patients recovered and were released from hospital. No complications, including cerebrospinal fluid leakage and infection occurred. During the follow-up of 1 - 4 years, 18 asymptomatic patients' neurological function were normal and there was no deterioration, 7 symptomatic patients improved. Among the 7 patients, 4 patients had higher function grades compared with their preoperative assessments, and the other stayed in the same grades but with symptoms improved. Magnetic resonance imaging showed no tethered cord in all the patients postoperatively.
For lipomyelomeningocele, early operation should be performed to prevent the development of neurological defect. It is safe and effective to adopt subtotal excision of lipomas, suture of spinal pia mater, and resection of terminal filum.
探讨儿童脂肪脊髓脊膜膨出的外科治疗方法及技术。
2004年1月至2007年3月,对25例年龄在2个月至6岁的脂肪脊髓脊膜膨出患儿进行手术治疗。所有患者均行磁共振成像及肌电图检查。手术包括脂肪瘤次全切除、脊髓软膜缝合及终丝切断术。采用霍夫曼脂肪脊髓脊膜膨出功能分级方案评估治疗效果。
术后所有患者均康复出院,未发生包括脑脊液漏及感染在内的并发症。在1至4年的随访中,18例无症状患者神经功能正常且无恶化,7例有症状患者病情改善。7例患者中,4例患者功能分级较术前提高,另3例患者功能分级不变但症状改善。术后磁共振成像显示所有患者均无脊髓栓系。
对于脂肪脊髓脊膜膨出,应早期手术以预防神经功能缺损的发展。采用脂肪瘤次全切除、脊髓软膜缝合及终丝切断术安全有效。