Wang Hong-wu, Zhou Yun-zhi, Li Dong-mei, Zou Heng, Li Jing, Zhang Nan
Department of Respiratory Medicine, China Meitan General Hospital, Beijing 100028, China.
Zhonghua Yi Xue Za Zhi. 2010 May 25;90(20):1411-5.
To evaluate the indications, techniques, outcomes and complications of metallic stent removals in patients with airway disorders.
A retrospective analysis was performed in 43 patients with 47 tracheobronchial stents. The airway stent retrieval was performed under the guidance of rigid or flexible bronchoscopy between November 2005 and November 2009. There were 25 cases with 27 Z-type stents (25 covered metallic stents, CMS; 2 uncovered metallic stents, UCMS) and 18 cases with 20 Nitinol stents (4 CMS, 16 UCMS). Excessive stent-related granuloma formation or recurrent tumor in patients with UCMS group was similar to those with CMS (94.4% vs 89.7%). Fracture of stents in patients with UCMS group was higher than that in CMS group (83.3% vs 10.3%, P < 0.01).
Thirty-eight of 47 (80.9%) stents (Z-type stents 85.2%, Nitinol 75.0%) were successfully removed. Among them, 15 stents (39.5%) were retrieved by rigid bronchoscopy and 23 (60.5%) stents by flexible bronchoscopy (20 under local anesthesia and 3 under pain-free anesthesia). 87.0% (20/23) Z-type CMS was removed with a retrieval hook by a flexible bronchoscopy under local anesthesia with an average duration of pre-removal stenting of (3.5 +/- 0.6) months while 80% (12/15) Nitinol UCMS removed by a rigid bronchoscopy under general anesthesia with an average duration of pre-removal stenting of (10.7 +/- 3.7) months. A successful retrieval of intact stents was achieved in 84.0% (21/25) of CMS while 92.3% (12/13) of UCMS had a retrieval of rupture stent or piecemeal. In all cases, major post-removal complications included profuse hemorrhage (n = 4) and mucosal tear (n = 15). No mortality occurred during the procedure.
The indications for endoscopic retrieval of metallic stents include excessive or recurrent granuloma formation or tumor, recurrence of stenosis after stenting, stent fracture and conclusion of treatment, 3 - 4 months post-stenting in patients with benign stenoses. CMS can be effectively and safely removed with a retrieval hook by flexible bronchoscopy under local anesthesia without any major sequel. UCMS may be successfully retrieved by rigid bronchoscopy under general anesthesia.
评估气道疾病患者金属支架取出术的适应证、技术、结果及并发症。
对43例置入47枚气管支气管支架的患者进行回顾性分析。2005年11月至2009年11月期间,在硬质或可弯曲支气管镜引导下进行气道支架取出术。其中25例置入27枚Z型支架(25枚覆膜金属支架,CMS;2枚非覆膜金属支架,UCMS),18例置入20枚镍钛合金支架(4枚CMS,16枚UCMS)。UCMS组患者支架相关肉芽肿过度形成或肿瘤复发情况与CMS组相似(94.4%对89.7%)。UCMS组患者支架断裂发生率高于CMS组(83.3%对10.3%,P<0.01)。
47枚支架中的38枚(80.9%)(Z型支架85.2%,镍钛合金支架75.0%)成功取出。其中,15枚支架(39.5%)通过硬质支气管镜取出,23枚(60.5%)通过可弯曲支气管镜取出(20例在局部麻醉下,3例在无痛麻醉下)。87.0%(20/23)的Z型CMS在局部麻醉下通过可弯曲支气管镜用取出钩取出,取出前支架置入平均时间为(3.5±0.6)个月,而80%(12/15)的镍钛合金UCMS在全身麻醉下通过硬质支气管镜取出,取出前支架置入平均时间为(10.7±3.7)个月。84.0%(21/25)的CMS成功完整取出,而92.3%(12/13)的UCMS取出的是破裂支架或碎片。所有病例中,取出后主要并发症包括大量出血(n=4)和黏膜撕裂(n=15)。手术过程中无死亡病例。
内镜下取出金属支架的适应证包括肉芽肿过度形成或复发、肿瘤复发、支架置入后狭窄复发、支架断裂及治疗结束,良性狭窄患者支架置入后3 - 4个月。CMS可在局部麻醉下通过可弯曲支气管镜用取出钩有效、安全地取出,无任何严重后遗症。UCMS可在全身麻醉下通过硬质支气管镜成功取出。