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良性疾病中覆膜自膨式金属气道支架的取出:适应证、技术及结果

Removal of covered self-expandable metallic airway stents in benign disorders: indications, technique, and outcomes.

作者信息

Noppen Marc, Stratakos Grigoris, D'Haese Jan, Meysman Marc, Vinken Walter

机构信息

Interventional Endoscopy Clinic, Respiratory Division, University Hospital AZ-VUB, Laarbeeklaan 101, B 1090 Brussels, Belgium.

出版信息

Chest. 2005 Feb;127(2):482-7. doi: 10.1378/chest.127.2.482.

Abstract

STUDY OBJECTIVES

To describe the technique and outcome of removal of self-expandable metallic airway stents (SEMAS) in a series of patients who underwent stenting for benign airway stenoses.

DESIGN AND SETTING

A retrospective cohort analysis of patients with benign airway disorders treated with SEMAS between 1997 and 2003, who presented with an indication for stent removal in a tertiary-care hospital, and referral interventional pulmonology clinic.

PATIENTS AND METHODS

During the study period, 49 SEMAS were inserted in 39 patients for treatment of benign airway disorders. Ten of these 39 patients (25.6%), bearing 12 covered stents, presented with an indication for stent removal. Data of these cases were extracted from electronic files kept in our institution archive.

RESULTS

Indications for stent removal included excessive or recurrent granuloma formation (five cases), recurrence of stenosis after stent failure (one case), stent fracture (two cases), and accomplishment of treatment (two cases). In all of these cases, covered versions of SEMAS had been placed either in the trachea or in a main bronchus. In contrast to many previous reports, these stents proved to be absolutely retrievable even if some difficulties were encountered. In all cases, however, removal was successful without major complications. All patients resumed normal spontaneous ventilation postoperatively, and follow-up was uneventful. Average duration of stenting before removal was 16.2 +/- 17.5 months (+/- SD) [range, 1 to 60 months].

CONCLUSIONS

We conclude that although placement of SEMAS is assumed to be permanent in patients with benign airway disorders, an indication for stent removal is often observed (25.6% in our series). The covered SEMAS can be effectively and safely removed if needed without major sequelae. Nevertheless, new technical improvements in metallic stent design and materials may help reinforce the concept of a retrievable metallic airway stent, which may offer significant clinical advantages.

摘要

研究目的

描述一系列因良性气道狭窄接受支架置入术的患者中取出自膨式金属气道支架(SEMAS)的技术及结果。

设计与背景

对1997年至2003年间接受SEMAS治疗的良性气道疾病患者进行回顾性队列分析,这些患者在一家三级医疗医院及转诊介入肺科诊所出现了取出支架的指征。

患者与方法

在研究期间,39例患者共置入49个SEMAS以治疗良性气道疾病。这39例患者中有10例(25.6%)携带12个覆膜支架,出现了取出支架的指征。这些病例的数据从我们机构存档的电子文件中提取。

结果

取出支架的指征包括肉芽肿形成过多或复发(5例)、支架失效后狭窄复发(1例)、支架断裂(2例)以及治疗完成(2例)。在所有这些病例中,覆膜SEMAS均放置于气管或主支气管。与之前许多报道不同,这些支架即便遇到一些困难,仍被证明是完全可取出的。然而,所有病例取出均成功,无重大并发症。所有患者术后恢复正常自主通气,随访情况良好。取出前平均支架置入时间为16.2±17.5个月(±标准差)[范围,1至60个月]。

结论

我们得出结论,尽管对于良性气道疾病患者,SEMAS的置入通常被认为是永久性的,但常可见到取出支架的指征(我们的系列研究中为25.6%)。如有需要,覆膜SEMAS可有效且安全地取出,无重大后遗症。尽管如此,金属支架设计和材料方面的新技术改进可能有助于强化可取出金属气道支架的概念,这可能带来显著的临床优势。

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