Faculty of Medicine, Suez Canal University, Ismailia, Egypt.
Diabetes Res Clin Pract. 2010 Sep;89(3):276-81. doi: 10.1016/j.diabres.2010.05.021. Epub 2010 Jun 19.
Honey is known, since antiquity, as an effective wound dressing. Emergence of resistant strains and the financial burden of modern dressings, have revived honey as cost-effective dressing particularly in developing countries. Its suitability for all stages of wound healing suggests its clinical effectiveness in diabetic foot wound infections. Thirty infected diabetic foot wounds were randomly selected from patients presenting to Surgery Department, Suez Canal University Hospital, Ismailia, Egypt. Honey dressing was applied to wounds for 3 months till healing, grafting or failure of treatment. Changes in grade and stage of wounds, using University of Texas Diabetic Wound Classification, as well as surface area were recorded weekly. Bacterial load was determined before and after honey dressing. Complete healing was significantly achieved in 43.3% of ulcers. Decrease in size and healthy granulation was significantly observed in another 43.3% of patients. Bacterial load of all ulcers was significantly reduced after the first week of honey dressing. Failure of treatment was observed in 6.7% of ulcers. This study proves that commercial clover honey is a clinical and cost-effective dressing for diabetic wound in developing countries. It is omnipresence and concordance with cultural beliefs makes it a typical environmentally based method for treating these conditions.
蜂蜜作为一种有效的伤口敷料,自古以来就为人所知。耐药菌株的出现和现代敷料的经济负担,使得蜂蜜作为一种具有成本效益的敷料重新受到关注,尤其是在发展中国家。它适用于伤口愈合的所有阶段,这表明它在糖尿病足感染中的临床疗效。从埃及伊斯梅利亚苏伊士运河大学医院外科部门就诊的患者中随机选择了 30 例感染性糖尿病足伤口。将蜂蜜敷料应用于伤口,持续 3 个月,直至愈合、植皮或治疗失败。每周记录伤口的等级和阶段(使用德克萨斯大学糖尿病伤口分类法)以及表面积的变化。在使用蜂蜜敷料前后测定细菌负荷。43.3%的溃疡完全愈合。另外 43.3%的患者溃疡大小和健康肉芽组织明显减少。所有溃疡的细菌负荷在使用蜂蜜敷料后的第一周明显降低。有 6.7%的溃疡治疗失败。本研究证明,商用三叶草蜂蜜是发展中国家糖尿病伤口的一种临床和经济有效的敷料。它无处不在,与文化信仰一致,使其成为治疗这些疾病的典型基于环境的方法。