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[Effect of isadrine and propranolol on the membrane potential of mammary secretory cells].

作者信息

Grachev I I, Toljunov Iu A, Markov A G

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1978 Mar;64(3):309-14.

PMID:206473
Abstract

1.10(-7)--1.10(-5) g/ml of isadrine induced a 2-phase hyperpolarization changes of MP of the secretory cell. Propranolol (1.10(-6) g/ml) decreased the amplitude of hyperpolarization response of the MP to oxytocin by 36%; 1.10(-9)--1.10(-8) g/ml of isadrine induced a 42% and 53% decrease respectively, and 1.10(-7)--1.10(-5) g/ml blocked the response of secretory cells to oxytocin. The data obtained suggest that catecholamines can effect the MP by means of interaction with beta-adrenoreceptors of mammary secretory cells.

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