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PharmGKB summary: very important pharmacogene information for CYP2B6.

作者信息

Thorn Caroline F, Lamba Jatinder K, Lamba Vishal, Klein Teri E, Altman Russ B

机构信息

Department of Genetics, Stanford University Medical Center, Stanford, California 94305-5120, USA.

出版信息

Pharmacogenet Genomics. 2010 Aug;20(8):520-3. doi: 10.1097/fpc.0b013e32833947c2.

Abstract
摘要

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本文引用的文献

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Pharmacokinetics of plasma efavirenz and CYP2B6 polymorphism in southern Chinese.
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Polymorphisms of drug-metabolizing enzymes (GST, CYP2B6 and CYP3A) affect the pharmacokinetics of thiotepa and tepa.
Br J Clin Pharmacol. 2009 Jan;67(1):50-60. doi: 10.1111/j.1365-2125.2008.03321.x. Epub 2008 Nov 17.
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CYP2B6: new insights into a historically overlooked cytochrome P450 isozyme.
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