Phattanachindakun Buraya, Boonyagulsrirung Tanong, Chanprapaph Pharuhas
Maternal and Fetal Medicine Division, Department of Obstetrics and Gynecology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
J Med Assoc Thai. 2010 Jul;93(7):759-64.
To determine the correlation between the rapid biophysical profile (rBPP), the combination of amniotic fluid index (AFI), and sound-provoked fetal movement (SPFM) detected by ultrasound, and the full biophysical profile (FBP) in terms of abnormal and normal result.
A prospective study was performed in 200 singleton pregnancies with no fetal anomalies between 30-42 weeks of gestation indicated for non-stress test (NST). All participants received both the standard (FBP) and the new rBPP examinations. Abnormal fetal test was defined as having a score of < or = 6 for FBP or < or = 2 for rBPP. The main outcome measurement was Spearman's correlation coefficient (r) between both examinations.
The incidences of the abnormal tests were 1.5% and 6.0% in FBP and rBPP, respectively. The data showed a positive correlation between the two tests (r(s) = 0.67; p < 0.01). Regarding the operative time, FBP assessment was 25.56 +/- 8.75 times longer than rBPP. The number of abnormal NST was remarked at 1.5% while oligohydramnios and abnormal SPFM were detected at 5% and 2%, respectively. Compared to the standard NST, rBPP test was significantly superior in terms of correlation with FBP (r(s) = 0.67 vs. 0.33) and shorter duration of test (1.21 +/- 0.32 min. vs. 21.65 +/- 5.47).
The statistically significant positive correlation between rBPP and FBP has been revealed. Due to its simplicity, rapidity, and no need of expensive equipment or experienced interpreter the rBPP may be alternatively used as a primary antepartum fetal test in the overcrowded obstetric center or when fetal surveillance tests are limited.
确定超声检测的快速生物物理评分（rBPP，即羊水指数[AFI]与声刺激胎儿运动[SPFM]的组合）与完整生物物理评分（FBP）在结果正常和异常方面的相关性。
对200例妊娠30 - 42周、无胎儿异常且因无应激试验（NST）而入选的单胎妊娠进行前瞻性研究。所有参与者均接受了标准的（FBP）和新的rBPP检查。异常胎儿检查定义为FBP评分≤6或rBPP评分≤2。主要观察指标是两种检查之间的Spearman相关系数（r）。
FBP和rBPP检查中异常检查的发生率分别为1.5%和6.0%。数据显示两种检查之间存在正相关（r(s)=0.67；p<0.01）。关于操作时间，FBP评估比rBPP长25.56±8.75倍。异常NST的发生率为1.5%，羊水过少和异常SPFM的检出率分别为5%和2%。与标准NST相比，rBPP检查在与FBP的相关性（r(s)=0.67对0.33）和检查持续时间较短（1.21±0.32分钟对21.65±5.47）方面明显更优。
已揭示rBPP与FBP之间存在统计学上显著的正相关。由于其简单、快速，且无需昂贵设备或经验丰富的解释人员，rBPP可在人满为患的产科中心或胎儿监测检查受限的情况下，用作产前胎儿的初步检查。
