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[天然生物聚合物作为药品剂型中的辅料。第一部分。软胶囊作为一种现代且精致的药物剂型]

[Natural biopolymers as excipients in medicinal product dosage form. Part I. Soft gelatin capsules as a modern and elegant pharmaceutical dosage form].

作者信息

Dobrzyński Łukasz Jerzy, Zgoda Marian Mikołaj

机构信息

Medana Pharma S.A., Łodzi.

出版信息

Polim Med. 2010;40(2):11-9.

Abstract

Soft gelatin capsules (Softgels) are modern and effective pharmaceutical dosage form for the administration of many medicinal products and food supplements formulations. In this short article major advantages and disadvantages of soft gelatin capsules are reviewed. Each step of manufacturing focused on fundamental techniques and requirements for developing and manufacturing technology for soft gelatin capsules is provided. Main role, characteristics, raw material, manufacturing techniques and applications in dosage form of gelatin is discussed. The review of recent advances in softgels are also included.

摘要

软胶囊是用于许多药品和食品补充剂配方给药的现代且有效的药物剂型。在这篇短文中,将对软胶囊的主要优缺点进行综述。文中提供了软胶囊开发和制造技术的每一步骤,重点介绍了基本技术和要求。讨论了明胶在剂型中的主要作用、特性、原材料、制造技术及应用。文中还包括了软胶囊最新进展的综述。

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