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退伍军人事务盐湖城综合健康诊所治疗慢性疼痛和与压力相关的抑郁、焦虑和创伤后应激障碍的结果评估。

Outcome evaluation of the Veterans Affairs Salt Lake City Integrative Health Clinic for chronic pain and stress-related depression, anxiety, and post-traumatic stress disorder.

机构信息

1 Department of Anesthesia, Veterans Affairs Health Care System, Integrative Health, Adjunct College of Nursing, University of Utah , Salt Lake City, UT.

出版信息

J Altern Complement Med. 2010 Aug;16(8):823-35. doi: 10.1089/acm.2009.0510.

Abstract

OBJECTIVES

The purpose of this longitudinal outcome research study was to determine the effectiveness of the Integrative Health Clinic and Program (IHCP) and to perform a subgroup analysis investigating patient benefit. The IHCP is an innovative clinical service within the Veterans Affairs Health Care System designed for nonpharmacologic biopsychosocial management of chronic nonmalignant pain and stress-related depression, anxiety, and symptoms of post-traumatic stress disorder (PTSD) utilizing complementary and alternative medicine and mind-body skills.

METHODS

A post-hoc quasi-experimental design was used and combined with subgroup analysis to determine who benefited the most from the program. Data were collected at intake and up to four follow-up visits over a 2-year time period. Hierarchical linear modeling was used for the statistical analysis. The outcome measures included: Health-Related Quality of Life (SF-36), the Beck Depression Inventory (BDI), and Beck Anxiety Inventory (BAI). Subgroup comparisons included low anxiety (BAI < 19, n = 82), low depression (BDI < 19, n = 93), and absence of PTSD (n = 102) compared to veterans with high anxiety (BAI > or = 19, n = 77), high depression (BDI > 19, n = 67), and presence of PTSD (n = 63).

RESULTS

All of the comparison groups demonstrated an improvement in depression and anxiety scores, as well as in some SF-36 categories. The subgroups with the greatest improvement, seen at 6 months, were found in the high anxiety group (Cohen's d = 0.52), the high-depression group (Cohen's d = 0.46), and the PTSD group (Cohen's d = 0.41).

CONCLUSIONS

The results suggest IHCP is an effective program, improving chronic pain and stress-related depression, anxiety, and health-related quality of life. Of particular interest was a significant improvement in anxiety in the PTSD group. The IHCP model offers innovative treatment options that are low risk, low cost, and acceptable to patients and providers.

摘要

目的

本纵向结局研究旨在确定综合健康诊所和计划(IHCP)的有效性,并进行亚组分析以调查患者获益。IHCP 是退伍军人事务医疗保健系统内的一项创新临床服务,旨在通过补充和替代医学以及身心技能,对慢性非恶性疼痛和与压力相关的抑郁、焦虑和创伤后应激障碍(PTSD)症状进行非药物的生物心理社会管理。

方法

采用事后准实验设计,并结合亚组分析,以确定谁从该计划中获益最多。数据在 2 年时间内,于入组时和最多 4 次随访时收集。使用分层线性建模进行统计分析。结果测量包括:健康相关生活质量(SF-36)、贝克抑郁量表(BDI)和贝克焦虑量表(BAI)。亚组比较包括低焦虑(BAI<19,n=82)、低抑郁(BDI<19,n=93)和无 PTSD(n=102)与高焦虑(BAI≥19,n=77)、高抑郁(BDI>19,n=67)和 PTSD 患者(n=63)进行比较。

结果

所有比较组的抑郁和焦虑评分均有所改善,一些 SF-36 类别也有所改善。在 6 个月时,观察到最大改善的亚组是高焦虑组(Cohen's d=0.52)、高抑郁组(Cohen's d=0.46)和 PTSD 组(Cohen's d=0.41)。

结论

结果表明 IHCP 是一种有效的计划,可以改善慢性疼痛和与压力相关的抑郁、焦虑和健康相关生活质量。特别有趣的是 PTSD 组的焦虑显著改善。IHCP 模式提供了创新的治疗选择,这些选择风险低、成本低,并且患者和提供者都能接受。

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